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Probing the Conformation of an IgG1 Monoclonal Antibody in Lyophilized Solids Using Solid-State Hydrogen-Deuterium Exchange with Mass Spectrometric Analysis (ssHDX-MS).
Moussa, Ehab M; Singh, Satish K; Kimmel, Michael; Nema, Sandeep; Topp, Elizabeth M.
Affiliation
  • Moussa EM; Department of Industrial and Physical Pharmacy, College of Pharmacy, Purdue University , West Lafayette, Indiana 47907, United States.
  • Singh SK; BioTherapeutics Pharmaceutical Sciences, Pfizer Inc. , Chesterfield, Missouri 63017, United States.
  • Kimmel M; BioTherapeutics Pharmaceutical Sciences, Pfizer Inc. , Chesterfield, Missouri 63017, United States.
  • Nema S; BioTherapeutics Pharmaceutical Sciences, Pfizer Inc. , Chesterfield, Missouri 63017, United States.
  • Topp EM; Department of Industrial and Physical Pharmacy, College of Pharmacy, Purdue University , West Lafayette, Indiana 47907, United States.
Mol Pharm ; 15(2): 356-368, 2018 02 05.
Article in En | MEDLINE | ID: mdl-29355022
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Full text: 1 Database: MEDLINE Main subject: Immunoglobulin G / Chemistry, Pharmaceutical / Antibodies, Monoclonal Language: En Journal: Mol Pharm Journal subject: BIOLOGIA MOLECULAR / FARMACIA / FARMACOLOGIA Year: 2018 Type: Article Affiliation country: United States
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Immunoglobulin G / Chemistry, Pharmaceutical / Antibodies, Monoclonal Language: En Journal: Mol Pharm Journal subject: BIOLOGIA MOLECULAR / FARMACIA / FARMACOLOGIA Year: 2018 Type: Article Affiliation country: United States