Phase Transitions in the Assembly and Function of Human miRISC.

Sheu-Gruttadauria, Jessica; MacRae, Ian J

Sheu-Gruttadauria, Jessica; MacRae, Ian J.

Affiliation

Sheu-Gruttadauria J; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
MacRae IJ; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA. Electronic address: macrae@scripps.edu.

Cell ; 173(4): 946-957.e16, 2018 05 03.

Article in En | MEDLINE | ID: mdl-29576456

Subject(s)

Argonaute Proteins/metabolism; MicroRNAs/metabolism; RNA-Binding Proteins/metabolism; Amino Acid Motifs; Argonaute Proteins/genetics; Binding Sites; Fluorescence Recovery After Photobleaching; HEK293 Cells; Humans; Phase Transition; Protein Binding; RNA, Messenger/metabolism; RNA-Binding Proteins/genetics; RNA-Induced Silencing Complex/metabolism

Key words

Argonaute; GW182; TNRC6; miRISC; miRNA; microRNA; molecular condensation; phase separation

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Database: MEDLINE Main subject: RNA-Binding Proteins / MicroRNAs / Argonaute Proteins Type of study: Prognostic_studies Limits: Humans Language: En Journal: Cell Year: 2018 Type: Article Affiliation country: United States

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google