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Age-dependent neurodegeneration and organelle transport deficiencies in mutant TDP43 patient-derived neurons are independent of TDP43 aggregation.
Kreiter, N; Pal, A; Lojewski, X; Corcia, P; Naujock, M; Reinhardt, P; Sterneckert, J; Petri, S; Wegner, F; Storch, A; Hermann, A.
Affiliation
  • Kreiter N; Department of Neurology, Technische Universität Dresden, Germany; German Center for Neurodegenerative Diseases (DZNE), Dresden, Germany.
  • Pal A; Department of Neurology, Technische Universität Dresden, Germany.
  • Lojewski X; Department of Neurology, Technische Universität Dresden, Germany.
  • Corcia P; Centre expert pour la SLA et les maladies du motoneurone, CHU Tours, 2 Boulevard Tonnelle, 37044 Tours CEDEX1, France.
  • Naujock M; Department of Neurology, Hannover Medical School, Hannover, Germany.
  • Reinhardt P; Center for Regenerative Therapies Dresden (CRTD), Technische Universität Dresden, Germany.
  • Sterneckert J; Center for Regenerative Therapies Dresden (CRTD), Technische Universität Dresden, Germany.
  • Petri S; Department of Neurology, Hannover Medical School, Hannover, Germany.
  • Wegner F; Department of Neurology, Hannover Medical School, Hannover, Germany.
  • Storch A; Department of Neurology, Technische Universität Dresden, Germany; German Center for Neurodegenerative Diseases (DZNE), Dresden, Germany; Center for Regenerative Therapies Dresden (CRTD), Technische Universität Dresden, Germany; Department of Neurology, University of Rostock, Rostock, Germany.
  • Hermann A; Department of Neurology, Technische Universität Dresden, Germany; German Center for Neurodegenerative Diseases (DZNE), Dresden, Germany; Center for Regenerative Therapies Dresden (CRTD), Technische Universität Dresden, Germany. Electronic address: Andreas.Hermann@uniklinikum-dresden.de.
Neurobiol Dis ; 115: 167-181, 2018 07.
Article in En | MEDLINE | ID: mdl-29630989
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Full text: 1 Database: MEDLINE Main subject: Aging / Organelles / Neurodegenerative Diseases / DNA-Binding Proteins / Protein Aggregates / Motor Neurons / Mutation Limits: Female / Humans / Male / Middle aged Language: En Journal: Neurobiol Dis Journal subject: NEUROLOGIA Year: 2018 Type: Article Affiliation country: Germany
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Full text: 1 Database: MEDLINE Main subject: Aging / Organelles / Neurodegenerative Diseases / DNA-Binding Proteins / Protein Aggregates / Motor Neurons / Mutation Limits: Female / Humans / Male / Middle aged Language: En Journal: Neurobiol Dis Journal subject: NEUROLOGIA Year: 2018 Type: Article Affiliation country: Germany