Three-dimensional collagenous niche and azacytidine selectively promote time-dependent cardiomyogenesis from human bone marrow-derived MSC spheroids.

Joshi, Jyotsna; Mahajan, Gautam; Kothapalli, Chandrasekhar R

Joshi, Jyotsna; Mahajan, Gautam; Kothapalli, Chandrasekhar R.

Affiliation

Joshi J; Department of Chemical and Biomedical Engineering, Cleveland State University, Cleveland, Ohio.
Mahajan G; Department of Chemical and Biomedical Engineering, Cleveland State University, Cleveland, Ohio.
Kothapalli CR; Department of Chemical and Biomedical Engineering, Cleveland State University, Cleveland, Ohio.

Biotechnol Bioeng ; 115(8): 2013-2026, 2018 08.

Article in En | MEDLINE | ID: mdl-29665002

Subject(s)

Azacitidine/metabolism; Bone Marrow Cells/drug effects; Cell Differentiation; Mesenchymal Stem Cells/drug effects; Myocytes, Cardiac/physiology; Spheroids, Cellular/physiology; Bone Marrow Cells/physiology; Cell Survival; Cells, Cultured; Collagen/metabolism; Humans; Mesenchymal Stem Cells/physiology

Key words

5-azacytidine; Wnt signaling; atomic force microscopy; collagen gels; human bone marrow-derived MSCs; myocardial infarction

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Full text: 1 Database: MEDLINE Main subject: Azacitidine / Bone Marrow Cells / Cell Differentiation / Spheroids, Cellular / Myocytes, Cardiac / Mesenchymal Stem Cells Limits: Humans Language: En Journal: Biotechnol Bioeng Year: 2018 Type: Article

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