MicroRNA-focused CRISPR-Cas9 library screen reveals fitness-associated miRNAs.

Kurata, Jessica S; Lin, Ren-Jang

Kurata, Jessica S; Lin, Ren-Jang.

Affiliation

Kurata JS; Department of Molecular and Cellular Biology, Beckman Research Institute of the City of Hope, Duarte, California 91010, USA.
Lin RJ; Irell and Manella Graduate School of Biological Sciences of the City of Hope, Duarte, California 91010, USA.

RNA ; 24(7): 966-981, 2018 07.

Article in En | MEDLINE | ID: mdl-29720387

Subject(s)

CRISPR-Cas Systems; MicroRNAs/genetics; Cell Line, Tumor; Female; Genome, Human; HeLa Cells; Humans; MicroRNAs/metabolism; Stomach Neoplasms/genetics; Stomach Neoplasms/metabolism; Uterine Cervical Neoplasms/genetics; Uterine Cervical Neoplasms/metabolism

Key words

CRISPR-Cas9; cancer; functional screening; microRNA; sgRNA library

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Full text: 1 Database: MEDLINE Main subject: MicroRNAs / CRISPR-Cas Systems Type of study: Risk_factors_studies Limits: Female / Humans Language: En Journal: RNA Journal subject: BIOLOGIA MOLECULAR Year: 2018 Type: Article Affiliation country: United States

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