Prospects for engineering dynamic CRISPR-Cas transcriptional circuits to improve bioproduction.

Fontana, Jason; Voje, William E; Zalatan, Jesse G; Carothers, James M

Fontana, Jason; Voje, William E; Zalatan, Jesse G; Carothers, James M.

Affiliation

Fontana J; Molecular Engineering and Sciences Institute and Center for Synthetic Biology, University of Washington, Seattle, WA, 98195, USA.
Voje WE; Molecular Engineering and Sciences Institute and Center for Synthetic Biology, University of Washington, Seattle, WA, 98195, USA.
Zalatan JG; Department of Chemical Engineering, University of Washington, Seattle, WA, 98195, USA.
Carothers JM; Molecular Engineering and Sciences Institute and Center for Synthetic Biology, University of Washington, Seattle, WA, 98195, USA. zalatan@uw.edu.

J Ind Microbiol Biotechnol ; 45(7): 481-490, 2018 Jul.

Article in En | MEDLINE | ID: mdl-29740742

Subject(s)

CRISPR-Cas Systems; Metabolic Engineering; Synthetic Biology; Corynebacterium glutamicum/genetics; Corynebacterium glutamicum/metabolism; Cyanobacteria/genetics; Cyanobacteria/metabolism; Escherichia coli/genetics; Escherichia coli/metabolism; Gene Expression Regulation; Genetic Engineering; Genome, Bacterial; Saccharomyces cerevisiae/genetics; Saccharomyces cerevisiae/metabolism; Transcription Factors/genetics; Transcription Factors/metabolism

Key words

Biosensors; CRISPRCas; Dynamic control; Metabolic engineering; Transcriptional control

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Full text: 1 Database: MEDLINE Main subject: Synthetic Biology / Metabolic Engineering / CRISPR-Cas Systems Language: En Journal: J Ind Microbiol Biotechnol Journal subject: BIOTECNOLOGIA / MICROBIOLOGIA Year: 2018 Type: Article Affiliation country: United States

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