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De novo biosynthesis of sterols and fatty acids in the Trypanosoma brucei procyclic form: Carbon source preferences and metabolic flux redistributions.
Millerioux, Yoann; Mazet, Muriel; Bouyssou, Guillaume; Allmann, Stefan; Kiema, Tiila-Riikka; Bertiaux, Eloïse; Fouillen, Laetitia; Thapa, Chandan; Biran, Marc; Plazolles, Nicolas; Dittrich-Domergue, Franziska; Crouzols, Aline; Wierenga, Rik K; Rotureau, Brice; Moreau, Patrick; Bringaud, Frédéric.
Affiliation
  • Millerioux Y; Laboratoire de Microbiologie Fondamentale et Pathogénicité (MFP), Université de Bordeaux, CNRS UMR-5234, Bordeaux, France.
  • Mazet M; Centre de Résonance Magnétique des Systèmes Biologiques (RMSB), Université de Bordeaux, CNRS UMR-5536, Bordeaux, France.
  • Bouyssou G; Laboratoire de Microbiologie Fondamentale et Pathogénicité (MFP), Université de Bordeaux, CNRS UMR-5234, Bordeaux, France.
  • Allmann S; Centre de Résonance Magnétique des Systèmes Biologiques (RMSB), Université de Bordeaux, CNRS UMR-5536, Bordeaux, France.
  • Kiema TR; Membrane Biogenesis Laboratory, CNRS-University of Bordeaux, UMR-5200, INRA Bordeaux Aquitaine, Villenave d'Ornon, France.
  • Bertiaux E; Laboratoire de Microbiologie Fondamentale et Pathogénicité (MFP), Université de Bordeaux, CNRS UMR-5234, Bordeaux, France.
  • Fouillen L; Centre de Résonance Magnétique des Systèmes Biologiques (RMSB), Université de Bordeaux, CNRS UMR-5536, Bordeaux, France.
  • Thapa C; Faculty of Biochemistry and Molecular Medicine, Biocenter Oulu, University of Oulu, Oulu, Finland.
  • Biran M; Trypanosome Transmission Group, Trypanosome Cell Biology Unit, Department of Parasites and Insect Vectors, INSERM U1201, Institut Pasteur, Paris, France.
  • Plazolles N; Membrane Biogenesis Laboratory, CNRS-University of Bordeaux, UMR-5200, INRA Bordeaux Aquitaine, Villenave d'Ornon, France.
  • Dittrich-Domergue F; Metabolome Facility of Bordeaux, Functional Genomics Center, Villenave d'Ornon.
  • Crouzols A; Faculty of Biochemistry and Molecular Medicine, Biocenter Oulu, University of Oulu, Oulu, Finland.
  • Wierenga RK; Centre de Résonance Magnétique des Systèmes Biologiques (RMSB), Université de Bordeaux, CNRS UMR-5536, Bordeaux, France.
  • Rotureau B; Laboratoire de Microbiologie Fondamentale et Pathogénicité (MFP), Université de Bordeaux, CNRS UMR-5234, Bordeaux, France.
  • Moreau P; Membrane Biogenesis Laboratory, CNRS-University of Bordeaux, UMR-5200, INRA Bordeaux Aquitaine, Villenave d'Ornon, France.
  • Bringaud F; Trypanosome Transmission Group, Trypanosome Cell Biology Unit, Department of Parasites and Insect Vectors, INSERM U1201, Institut Pasteur, Paris, France.
PLoS Pathog ; 14(5): e1007116, 2018 05.
Article in En | MEDLINE | ID: mdl-29813135
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Full text: 1 Database: MEDLINE Main subject: Sterols / Trypanosoma brucei brucei / Carbon / Fatty Acids Limits: Animals Language: En Journal: PLoS Pathog Year: 2018 Type: Article Affiliation country: France
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Full text: 1 Database: MEDLINE Main subject: Sterols / Trypanosoma brucei brucei / Carbon / Fatty Acids Limits: Animals Language: En Journal: PLoS Pathog Year: 2018 Type: Article Affiliation country: France