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Antibody-mediated stabilization of NRG1 induces behavioral and electrophysiological alterations in adult mice.
Dominguez, Sara L; Hegde, Ganapati V; Hanson, Jesse E; Xiang, Hong; Mandikian, Danielle; Boswell, C Andrew; Chiu, Cecilia; Wu, Yan; Tsai, Siao Ping; Fleck, Daniel; Weber, Martin; Ngu, Hai; Scearce-Levie, Kimberly; Jackson, Erica L.
Affiliation
  • Dominguez SL; Genentech, Neuroscience, South San Francisco, 94080, USA.
  • Hegde GV; Genentech, Discovery Oncology, South San Francisco, 94080, USA.
  • Hanson JE; ORIC Pharmaceuticals, Oncology, South San Francisco, CA, 94010, USA.
  • Xiang H; Genentech, Neuroscience, South San Francisco, 94080, USA.
  • Mandikian D; Genentech, Developmental Sciences, South San Francisco, 94080, USA.
  • Boswell CA; Genentech, Developmental Sciences, South San Francisco, 94080, USA.
  • Chiu C; Genentech, Developmental Sciences, South San Francisco, 94080, USA.
  • Wu Y; Genentech, Antibody Engineering, South San Francisco, 94080, USA.
  • Tsai SP; Genentech, Antibody Engineering, South San Francisco, 94080, USA.
  • Fleck D; Genentech, Biochemical and Cellular Oncology, South San Francisco, 94080, USA.
  • Weber M; Genentech, Neuroscience, South San Francisco, 94080, USA.
  • Ngu H; Genentech, Neuroscience, South San Francisco, 94080, USA.
  • Scearce-Levie K; Genentech, Pathology, South San Francisco, 94080, USA.
  • Jackson EL; Genentech, Neuroscience, South San Francisco, 94080, USA.
Sci Rep ; 8(1): 8239, 2018 05 29.
Article in En | MEDLINE | ID: mdl-29844389
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Full text: 1 Database: MEDLINE Main subject: Schizophrenia / Central Nervous System / Neuregulin-1 / Electrophysiology Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Journal: Sci Rep Year: 2018 Type: Article Affiliation country: United States
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Full text: 1 Database: MEDLINE Main subject: Schizophrenia / Central Nervous System / Neuregulin-1 / Electrophysiology Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Animals / Humans Language: En Journal: Sci Rep Year: 2018 Type: Article Affiliation country: United States