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An open-Label, 2 × 2 factorial, randomized controlled trial to evaluate the safety of apixaban vs. vitamin K antagonist and aspirin vs. placebo in patients with atrial fibrillation and acute coronary syndrome and/or percutaneous coronary intervention: Rationale and design of the AUGUSTUS trial.
Lopes, Renato D; Vora, Amit N; Liaw, Danny; Granger, Christopher B; Darius, Harald; Goodman, Shaun G; Mehran, Roxana; Windecker, Stephan; Alexander, John H.
Affiliation
  • Lopes RD; Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC. Electronic address: renato.lopes@dm.duke.edu.
  • Vora AN; Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC.
  • Liaw D; Bristol-Myers Squibb, Princeton, NJ.
  • Granger CB; Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC.
  • Darius H; Vivantes Neukoelln Medical Center, Berlin, Germany.
  • Goodman SG; Terrence Donnelly Heart Center, St Michael's Hospital, University of Toronto, Ontario, and Canadian VIGOUR Centre, University of Alberta, Edmonton, Canada.
  • Mehran R; Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, and Cardiovascular Research Foundation, New York, NY.
  • Windecker S; Swiss Cardiovascular Center, Bern, Switzerland.
  • Alexander JH; Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC.
Am Heart J ; 200: 17-23, 2018 06.
Article in En | MEDLINE | ID: mdl-29898844
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Full text: 1 Database: MEDLINE Main subject: Pyrazoles / Pyridones / Atrial Fibrillation / Warfarin / Stroke / Acute Coronary Syndrome / Percutaneous Coronary Intervention / Hemorrhage Type of study: Clinical_trials / Etiology_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Am Heart J Year: 2018 Type: Article
Fulltext
Add to My VHL
Print
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Full text: 1 Database: MEDLINE Main subject: Pyrazoles / Pyridones / Atrial Fibrillation / Warfarin / Stroke / Acute Coronary Syndrome / Percutaneous Coronary Intervention / Hemorrhage Type of study: Clinical_trials / Etiology_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Am Heart J Year: 2018 Type: Article