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Inherited disorders of cobalamin metabolism disrupt nucleocytoplasmic transport of mRNA through impaired methylation/phosphorylation of ELAVL1/HuR.
Battaglia-Hsu, Shyue-Fang; Ghemrawi, Rose; Coelho, David; Dreumont, Natacha; Mosca, Pauline; Hergalant, Sébastien; Gauchotte, Guillaume; Sequeira, Jeffrey M; Ndiongue, Mariam; Houlgatte, Rémi; Alberto, Jean-Marc; Umoret, Remy; Robert, Aurélie; Paoli, Justine; Jung, Martin; Quadros, Edward V; Guéant, Jean-Louis.
Affiliation
  • Battaglia-Hsu SF; INSERM UMRS 954 NGERE - Nutrition, Genetics, and Environmental Risk Exposure and National Center of Inborn Errors of Metabolism, Faculty of Medicine of Nancy, University of Lorraine and University Regional Hospital Center of Nancy, Vandoeuvre-lès-Nancy, F-54000, France.
  • Ghemrawi R; INSERM UMRS 954 NGERE - Nutrition, Genetics, and Environmental Risk Exposure and National Center of Inborn Errors of Metabolism, Faculty of Medicine of Nancy, University of Lorraine and University Regional Hospital Center of Nancy, Vandoeuvre-lès-Nancy, F-54000, France.
  • Coelho D; INSERM UMRS 954 NGERE - Nutrition, Genetics, and Environmental Risk Exposure and National Center of Inborn Errors of Metabolism, Faculty of Medicine of Nancy, University of Lorraine and University Regional Hospital Center of Nancy, Vandoeuvre-lès-Nancy, F-54000, France.
  • Dreumont N; INSERM UMRS 954 NGERE - Nutrition, Genetics, and Environmental Risk Exposure and National Center of Inborn Errors of Metabolism, Faculty of Medicine of Nancy, University of Lorraine and University Regional Hospital Center of Nancy, Vandoeuvre-lès-Nancy, F-54000, France.
  • Mosca P; INSERM UMRS 954 NGERE - Nutrition, Genetics, and Environmental Risk Exposure and National Center of Inborn Errors of Metabolism, Faculty of Medicine of Nancy, University of Lorraine and University Regional Hospital Center of Nancy, Vandoeuvre-lès-Nancy, F-54000, France.
  • Hergalant S; INSERM UMRS 954 NGERE - Nutrition, Genetics, and Environmental Risk Exposure and National Center of Inborn Errors of Metabolism, Faculty of Medicine of Nancy, University of Lorraine and University Regional Hospital Center of Nancy, Vandoeuvre-lès-Nancy, F-54000, France.
  • Gauchotte G; INSERM UMRS 954 NGERE - Nutrition, Genetics, and Environmental Risk Exposure and National Center of Inborn Errors of Metabolism, Faculty of Medicine of Nancy, University of Lorraine and University Regional Hospital Center of Nancy, Vandoeuvre-lès-Nancy, F-54000, France.
  • Sequeira JM; Division of Hematology/Oncology, Department of Medicine, SUNY-Downstate Medical Center, Brooklyn, New York, NY, USA.
  • Ndiongue M; INSERM UMRS 954 NGERE - Nutrition, Genetics, and Environmental Risk Exposure and National Center of Inborn Errors of Metabolism, Faculty of Medicine of Nancy, University of Lorraine and University Regional Hospital Center of Nancy, Vandoeuvre-lès-Nancy, F-54000, France.
  • Houlgatte R; INSERM UMRS 954 NGERE - Nutrition, Genetics, and Environmental Risk Exposure and National Center of Inborn Errors of Metabolism, Faculty of Medicine of Nancy, University of Lorraine and University Regional Hospital Center of Nancy, Vandoeuvre-lès-Nancy, F-54000, France.
  • Alberto JM; INSERM UMRS 954 NGERE - Nutrition, Genetics, and Environmental Risk Exposure and National Center of Inborn Errors of Metabolism, Faculty of Medicine of Nancy, University of Lorraine and University Regional Hospital Center of Nancy, Vandoeuvre-lès-Nancy, F-54000, France.
  • Umoret R; INSERM UMRS 954 NGERE - Nutrition, Genetics, and Environmental Risk Exposure and National Center of Inborn Errors of Metabolism, Faculty of Medicine of Nancy, University of Lorraine and University Regional Hospital Center of Nancy, Vandoeuvre-lès-Nancy, F-54000, France.
  • Robert A; INSERM UMRS 954 NGERE - Nutrition, Genetics, and Environmental Risk Exposure and National Center of Inborn Errors of Metabolism, Faculty of Medicine of Nancy, University of Lorraine and University Regional Hospital Center of Nancy, Vandoeuvre-lès-Nancy, F-54000, France.
  • Paoli J; INSERM UMRS 954 NGERE - Nutrition, Genetics, and Environmental Risk Exposure and National Center of Inborn Errors of Metabolism, Faculty of Medicine of Nancy, University of Lorraine and University Regional Hospital Center of Nancy, Vandoeuvre-lès-Nancy, F-54000, France.
  • Jung M; Department of Medical Biochemistry and Molecular Biology, Saarland University, Building 44, Homburg 66421, Germany.
  • Quadros EV; Division of Hematology/Oncology, Department of Medicine, SUNY-Downstate Medical Center, Brooklyn, New York, NY, USA.
  • Guéant JL; INSERM UMRS 954 NGERE - Nutrition, Genetics, and Environmental Risk Exposure and National Center of Inborn Errors of Metabolism, Faculty of Medicine of Nancy, University of Lorraine and University Regional Hospital Center of Nancy, Vandoeuvre-lès-Nancy, F-54000, France.
Nucleic Acids Res ; 46(15): 7844-7857, 2018 09 06.
Article in En | MEDLINE | ID: mdl-30016500
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Full text: 1 Database: MEDLINE Main subject: Vitamin B 12 / Biological Transport / RNA-Binding Proteins / Receptors, Cytoplasmic and Nuclear / Karyopherins / ELAV-Like Protein 1 / Metabolic Diseases Limits: Animals / Humans Language: En Journal: Nucleic Acids Res Year: 2018 Type: Article Affiliation country: France
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Full text: 1 Database: MEDLINE Main subject: Vitamin B 12 / Biological Transport / RNA-Binding Proteins / Receptors, Cytoplasmic and Nuclear / Karyopherins / ELAV-Like Protein 1 / Metabolic Diseases Limits: Animals / Humans Language: En Journal: Nucleic Acids Res Year: 2018 Type: Article Affiliation country: France