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In vivo positive mutagenicity of 1,4-dioxane and quantitative analysis of its mutagenicity and carcinogenicity in rats.
Gi, Min; Fujioka, Masaki; Kakehashi, Anna; Okuno, Takahiro; Masumura, Kenichi; Nohmi, Takehiko; Matsumoto, Michiharu; Omori, Masako; Wanibuchi, Hideki; Fukushima, Shoji.
Affiliation
  • Gi M; Department of Molecular Pathology, Osaka City University Graduate School of Medicine, 1-4-3 Asahi-machi, Abeno-ku, Osaka, 545-8585, Japan.
  • Fujioka M; Department of Molecular Pathology, Osaka City University Graduate School of Medicine, 1-4-3 Asahi-machi, Abeno-ku, Osaka, 545-8585, Japan.
  • Kakehashi A; Department of Molecular Pathology, Osaka City University Graduate School of Medicine, 1-4-3 Asahi-machi, Abeno-ku, Osaka, 545-8585, Japan.
  • Okuno T; Department of Molecular Pathology, Osaka City University Graduate School of Medicine, 1-4-3 Asahi-machi, Abeno-ku, Osaka, 545-8585, Japan.
  • Masumura K; Division of Genetics and Mutagenesis, National Institute of Health Sciences, 3-25-26 Tonomachi, Kawasaki-ku, Kawasaki-shi, Kanagawa, 210-9501, Japan.
  • Nohmi T; Biological Safety Research Center, National Institute of Health Sciences, 3-25-26 Tonomachi, Kawasaki-ku, Kawasaki-shi, Kanagawa, 210-9501, Japan.
  • Matsumoto M; Japan Bioassay Research Center, Japan Organization of Occupational Health and Safety, Hadano, Kanagawa, 257-0015, Japan.
  • Omori M; Association for Promotion of Research on Risk Assessment, Nakagawa-ku, Nagoya, 454-0869, Japan.
  • Wanibuchi H; Department of Molecular Pathology, Osaka City University Graduate School of Medicine, 1-4-3 Asahi-machi, Abeno-ku, Osaka, 545-8585, Japan.
  • Fukushima S; Japan Bioassay Research Center, Japan Organization of Occupational Health and Safety, Hadano, Kanagawa, 257-0015, Japan. anhyohken@cloud-line.net.
Arch Toxicol ; 92(10): 3207-3221, 2018 10.
Article in En | MEDLINE | ID: mdl-30155721
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Full text: 1 Database: MEDLINE Main subject: Carcinogens / Dioxanes / Liver / Mutagens Type of study: Risk_factors_studies Limits: Animals Language: En Journal: Arch Toxicol Year: 2018 Type: Article Affiliation country: Japan
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Full text: 1 Database: MEDLINE Main subject: Carcinogens / Dioxanes / Liver / Mutagens Type of study: Risk_factors_studies Limits: Animals Language: En Journal: Arch Toxicol Year: 2018 Type: Article Affiliation country: Japan