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HMGA2 promotes intestinal tumorigenesis by facilitating MDM2-mediated ubiquitination and degradation of p53.
Wang, Yuhong; Hu, Lin; Wang, Jian; Li, Xiangwei; Sahengbieke, Sana; Wu, Jingjing; Lai, Maode.
Affiliation
  • Wang Y; Department of Pathology, Zhejiang University School of Medicine, Hangzhou, Zhejiang, PR China.
  • Hu L; Key Laboratory of Disease Proteomics of Zhejiang Province, Hangzhou, Zhejiang, China.
  • Wang J; Jiangsu Key Laboratory of Infection and Immunity, Institutes of Biology and Medical Sciences, Soochow University, Suzhou, Jiangsu, PR China.
  • Li X; Department of Surgical Oncology, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, PR China.
  • Sahengbieke S; Department of Pathology, Zhejiang University School of Medicine, Hangzhou, Zhejiang, PR China.
  • Wu J; Key Laboratory of Disease Proteomics of Zhejiang Province, Hangzhou, Zhejiang, China.
  • Lai M; Department of Pathology, Zhejiang University School of Medicine, Hangzhou, Zhejiang, PR China.
J Pathol ; 246(4): 508-518, 2018 12.
Article in En | MEDLINE | ID: mdl-30175854
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Full text: 1 Database: MEDLINE Main subject: Colorectal Neoplasms / Tumor Suppressor Protein p53 / HMGA2 Protein / Proto-Oncogene Proteins c-mdm2 Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Animals / Female / Humans / Male / Middle aged Language: En Journal: J Pathol Year: 2018 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Colorectal Neoplasms / Tumor Suppressor Protein p53 / HMGA2 Protein / Proto-Oncogene Proteins c-mdm2 Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Animals / Female / Humans / Male / Middle aged Language: En Journal: J Pathol Year: 2018 Type: Article