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An exploratory study by DMET array identifies a germline signature associated with imatinib response in gastrointestinal stromal tumor.
Ravegnini, Gloria; Urbini, Milena; Simeon, Vittorio; Genovese, Chiara; Astolfi, Annalisa; Nannini, Margherita; Gatto, Lidia; Saponara, Maristella; Ianni, Manuela; Indio, Valentina; Brandi, Giovanni; Trino, Stefania; Hrelia, Patrizia; Biasco, Guido; Angelini, Sabrina; Pantaleo, Maria A.
Affiliation
  • Ravegnini G; Department of Pharmacy and Biotechnology, University of Bologna, Bologna, Italy.
  • Urbini M; "Giorgio Prodi" Cancer Research Center, University of Bologna, Bologna, Italy.
  • Simeon V; Medical Statistics Unit, University of Campania "Luigi Vanvitelli", Napoli, Italy.
  • Genovese C; "Giorgio Prodi" Cancer Research Center, University of Bologna, Bologna, Italy.
  • Astolfi A; "Giorgio Prodi" Cancer Research Center, University of Bologna, Bologna, Italy.
  • Nannini M; Department of Specialized, Experimental and Diagnostic Medicine, Sant'Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.
  • Gatto L; Department of Specialized, Experimental and Diagnostic Medicine, Sant'Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.
  • Saponara M; Department of Specialized, Experimental and Diagnostic Medicine, Sant'Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.
  • Ianni M; "Giorgio Prodi" Cancer Research Center, University of Bologna, Bologna, Italy.
  • Indio V; "Giorgio Prodi" Cancer Research Center, University of Bologna, Bologna, Italy.
  • Brandi G; Department of Specialized, Experimental and Diagnostic Medicine, Sant'Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.
  • Trino S; Laboratory of Pre-Clinical and Translational Research Reference Cancer Center of Basilicata, Scientific Institute of Hospitalization and treatment, Rionero in Vulture, Potenza, Italy.
  • Hrelia P; Department of Pharmacy and Biotechnology, University of Bologna, Bologna, Italy.
  • Biasco G; "Giorgio Prodi" Cancer Research Center, University of Bologna, Bologna, Italy.
  • Angelini S; Medical Statistics Unit, University of Campania "Luigi Vanvitelli", Napoli, Italy.
  • Pantaleo MA; Department of Specialized, Experimental and Diagnostic Medicine, Sant'Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.
Pharmacogenomics J ; 19(4): 390-400, 2019 08.
Article in En | MEDLINE | ID: mdl-30237583
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Full text: 1 Database: MEDLINE Main subject: Polymorphism, Single Nucleotide / Gastrointestinal Stromal Tumors / Imatinib Mesylate / Germ Cells / Antineoplastic Agents Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Pharmacogenomics J Journal subject: BIOLOGIA MOLECULAR / FARMACOLOGIA Year: 2019 Type: Article Affiliation country: Italy
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Full text: 1 Database: MEDLINE Main subject: Polymorphism, Single Nucleotide / Gastrointestinal Stromal Tumors / Imatinib Mesylate / Germ Cells / Antineoplastic Agents Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Pharmacogenomics J Journal subject: BIOLOGIA MOLECULAR / FARMACOLOGIA Year: 2019 Type: Article Affiliation country: Italy