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Pyrrolo[2,1-c][1,4] benzodiazepine-3,11-diones protect SHSY-5Y cells from Cd-induced apoptosis involving suppression of endoplasmic reticulum stress.
Ma, Chao; Du, Ke; Zhao, Ying; Zhang, Linkui; Hu, Baichun; Cheng, Maosheng.
Affiliation
  • Ma C; Key Laboratory of Structure-Based Drugs Design & Discovery of Ministry of Education, School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang, China.
  • Du K; School of Pharmacy, Department of Pharmacology, China Medical University, Shenyang, China.
  • Zhao Y; Key Laboratory of Structure-Based Drugs Design & Discovery of Ministry of Education, School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang, China.
  • Zhang L; Key Laboratory of Structure-Based Drugs Design & Discovery of Ministry of Education, School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang, China.
  • Hu B; Key Laboratory of Structure-Based Drugs Design & Discovery of Ministry of Education, School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang, China.
  • Cheng M; Key Laboratory of Structure-Based Drugs Design & Discovery of Ministry of Education, School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang, China. Electronic address: mscheng@syphu.edu.cn.
Bioorg Med Chem ; 26(18): 5151-5158, 2018 10 01.
Article in En | MEDLINE | ID: mdl-30243792
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Full text: 1 Database: MEDLINE Main subject: Pyrroles / Benzodiazepines / Cadmium / Apoptosis / Endoplasmic Reticulum Stress Limits: Humans Language: En Journal: Bioorg Med Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2018 Type: Article Affiliation country: China
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Full text: 1 Database: MEDLINE Main subject: Pyrroles / Benzodiazepines / Cadmium / Apoptosis / Endoplasmic Reticulum Stress Limits: Humans Language: En Journal: Bioorg Med Chem Journal subject: BIOQUIMICA / QUIMICA Year: 2018 Type: Article Affiliation country: China