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SnapShot: RNA Structure Probing Technologies.
Carlson, Paul D; Evans, Molly E; Yu, Angela M; Strobel, Eric J; Lucks, Julius B.
Affiliation
  • Carlson PD; Robert F. Smith School of Chemical and Biomolecular Engineering, Cornell University, Ithaca NY; Center for Synthetic Biology, Northwestern University, Evanston IL.
  • Evans ME; Department of Chemical and Biological Engineering, Northwestern University, Evanston IL.
  • Yu AM; Center for Synthetic Biology, Northwestern University, Evanston IL; Tri-institutional Training Program in Computational Biology and Medicine, Weill Cornell Medicine, New York, NY.
  • Strobel EJ; Department of Chemical and Biological Engineering, Northwestern University, Evanston IL.
  • Lucks JB; Center for Synthetic Biology, Northwestern University, Evanston IL; Department of Chemical and Biological Engineering, Northwestern University, Evanston IL.
Cell ; 175(2): 600-600.e1, 2018 10 04.
Article in En | MEDLINE | ID: mdl-30290145
ABSTRACT
Chemical probing coupled to high-throughput sequencing offers a flexible approach to uncover many aspects of RNA structure relevant to its cellular function. With a wide variety of chemical probes available that each report on different features of RNA molecules, a broad toolkit exists for investigating in vivo and in vitro RNA structure and interactions with other molecules.
Subject(s)

Full text: 1 Database: MEDLINE Main subject: RNA / High-Throughput Nucleotide Sequencing Limits: Animals / Humans Language: En Journal: Cell Year: 2018 Type: Article

Full text: 1 Database: MEDLINE Main subject: RNA / High-Throughput Nucleotide Sequencing Limits: Animals / Humans Language: En Journal: Cell Year: 2018 Type: Article