Choosing Appropriate Solvents for ASD Preparation.

Luebbert, Christian; Real, Daniel; Sadowski, Gabriele

Luebbert, Christian; Real, Daniel; Sadowski, Gabriele.

Affiliation

Luebbert C; Department of Biochemical and Chemical Engineering, Laboratory of Thermodynamics , TU Dortmund University , Emil-Figge-Str. 70 , D-44227 Dortmund , Germany.
Real D; Department of Biochemical and Chemical Engineering, Laboratory of Thermodynamics , TU Dortmund University , Emil-Figge-Str. 70 , D-44227 Dortmund , Germany.
Sadowski G; Department of Biochemical and Chemical Engineering, Laboratory of Thermodynamics , TU Dortmund University , Emil-Figge-Str. 70 , D-44227 Dortmund , Germany.

Mol Pharm ; 15(11): 5397-5409, 2018 11 05.

Article in En | MEDLINE | ID: mdl-30335401

Subject(s)

Drug Compounding/methods; Excipients/chemistry; Models, Chemical; Solvents/chemistry; Calorimetry, Differential Scanning; Chemistry, Pharmaceutical; Crystallization; Desiccation/methods; Transition Temperature

Key words

PC-SAFT; amorphous phase separation; amorphous solid dispersion; homogeneity; organic solvent; spray drying

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Full text: 1 Database: MEDLINE Main subject: Solvents / Drug Compounding / Excipients / Models, Chemical Type of study: Prognostic_studies Language: En Journal: Mol Pharm Journal subject: BIOLOGIA MOLECULAR / FARMACIA / FARMACOLOGIA Year: 2018 Type: Article Affiliation country: Germany

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