Oncostatic treatment effect of triple negative breast cancer cell line with copper (I)-nicotinate complex.

Abdel-Mohsen, Mohamed A; Toson, Elshahat A; Helal, Marihan A

Abdel-Mohsen, Mohamed A; Toson, Elshahat A; Helal, Marihan A.

Affiliation

Abdel-Mohsen MA; Department of Applied Medical Chemistry, Medical Research Institute, Alexandria University, Alexandria, Egypt.
Toson EA; Department of Chemistry, Faculty of Science, Damietta University, Damietta, Egypt.
Helal MA; Department of Chemistry, Faculty of Science, Damietta University, Damietta, Egypt.

J Cell Biochem ; 120(3): 4278-4290, 2019 03.

Article in En | MEDLINE | ID: mdl-30362603

Subject(s)

Antineoplastic Agents/pharmacology; Antioxidants/pharmacology; Copper/pharmacology; Niacin/pharmacology; Triple Negative Breast Neoplasms/metabolism; Antineoplastic Agents/chemistry; Antioxidants/chemistry; Apoptosis/drug effects; Caspase 3/metabolism; Cell Cycle Checkpoints/drug effects; Cell Line, Tumor; Cell Survival/drug effects; Checkpoint Kinase 1/metabolism; Copper/chemistry; Female; Gene Expression; Humans; Niacin/chemistry; Phosphorylation/drug effects; Programmed Cell Death 1 Receptor; Superoxide Dismutase/metabolism; Survivin/genetics; Triple Negative Breast Neoplasms/pathology

Key words

apoptosis; caspase-3; copper (I)-nicotinate complex (CNC); programmed cell death protein-1 (PD-1); survivin; triple-negative breast cancer (TNBC)

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Full text: 1 Database: MEDLINE Main subject: Copper / Triple Negative Breast Neoplasms / Niacin / Antineoplastic Agents / Antioxidants Limits: Female / Humans Language: En Journal: J Cell Biochem Year: 2019 Type: Article Affiliation country: Egypt

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