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Positive N-Methyl-D-Aspartate Receptor Modulation by Rapastinel Promotes Rapid and Sustained Antidepressant-Like Effects.
Donello, John E; Banerjee, Pradeep; Li, Yong-Xin; Guo, Yuan-Xing; Yoshitake, Takashi; Zhang, Xiao-Lei; Miry, Omid; Kehr, Jan; Stanton, Patric K; Gross, Amanda L; Burgdorf, Jeffery S; Kroes, Roger A; Moskal, Joseph R.
Affiliation
  • Donello JE; Allergan, Plc, Irvine, California.
  • Banerjee P; Allergan, Plc, Madison, New Jersey.
  • Li YX; Allergan, Plc, Irvine, California.
  • Guo YX; Allergan, Plc, Irvine, California.
  • Yoshitake T; Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.
  • Zhang XL; Department of Cell Biology and Anatomy, New York Medical College, Valhalla, New York.
  • Miry O; Department of Cell Biology and Anatomy, New York Medical College, Valhalla, New York.
  • Kehr J; Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden.
  • Stanton PK; Pronexus Analytical AB, Bromma, Sweden.
  • Gross AL; Department of Cell Biology and Anatomy, New York Medical College, Valhalla, New York.
  • Burgdorf JS; Aptinyx, Inc., Evanston, Illinois.
  • Kroes RA; Falk Center for Molecular Therapeutics, Department of Biomedical Engineering, McCormick School of Engineering and Applied Sciences, Northwestern University, Evanston, Illinois.
  • Moskal JR; Aptinyx, Inc., Evanston, Illinois.
Int J Neuropsychopharmacol ; 22(3): 247-259, 2019 03 01.
Article in En | MEDLINE | ID: mdl-30544218

Full text: 1 Database: MEDLINE Main subject: Oligopeptides / Cerebral Cortex / Receptors, N-Methyl-D-Aspartate / Antidepressive Agents Limits: Animals Language: En Journal: Int J Neuropsychopharmacol Journal subject: NEUROLOGIA / PSICOFARMACOLOGIA Year: 2019 Type: Article

Full text: 1 Database: MEDLINE Main subject: Oligopeptides / Cerebral Cortex / Receptors, N-Methyl-D-Aspartate / Antidepressive Agents Limits: Animals Language: En Journal: Int J Neuropsychopharmacol Journal subject: NEUROLOGIA / PSICOFARMACOLOGIA Year: 2019 Type: Article