Transfer of Synthetic Human Chromosome into Human Induced Pluripotent Stem Cells for Biomedical Applications.

Sinenko, Sergey A; Skvortsova, Elena V; Liskovykh, Mikhail A; Ponomartsev, Sergey V; Kuzmin, Andrey A; Khudiakov, Aleksandr A; Malashicheva, Anna B; Alenina, Natalia; Larionov, Vladimir; Kouprina, Natalay; Tomilin, Alexey N

Sinenko, Sergey A; Skvortsova, Elena V; Liskovykh, Mikhail A; Ponomartsev, Sergey V; Kuzmin, Andrey A; Khudiakov, Aleksandr A; Malashicheva, Anna B; Alenina, Natalia; Larionov, Vladimir; Kouprina, Natalay; Tomilin, Alexey N.

Affiliation

Sinenko SA; Institute of Cytology, Russian Academy of Sciences, 4 Tikhoretsky Ave., St-Petersburg 194064, Russia. s.sinenko@incras.ru.
Skvortsova EV; Division of Molecular and Radiation Biophysics, Petersburg Nuclear Physics Institute named by B.P. Konstantinov of National Research Centre "Kurchatov Institute", Orlova Roscha 1, Gatchina 188300, Russia. s.sinenko@incras.ru.
Liskovykh MA; Institute of Cytology, Russian Academy of Sciences, 4 Tikhoretsky Ave., St-Petersburg 194064, Russia. e.skvortsova@incras.ru.
Ponomartsev SV; Developmental Therapeutics Branch, National Cancer Institute, Bethesda, MD 20892, USA. mikhail.liskovykh@nih.gov.
Kuzmin AA; Institute of Cytology, Russian Academy of Sciences, 4 Tikhoretsky Ave., St-Petersburg 194064, Russia. s.ponomartsev@incras.ru.
Khudiakov AA; Institute of Cytology, Russian Academy of Sciences, 4 Tikhoretsky Ave., St-Petersburg 194064, Russia. a.kuzmin@incras.ru.
Malashicheva AB; Almazov National Medical Research Centre, 2 Akkuratova Str., St-Petersburg 197341, Russia. hudiakov.aa@gmail.com.
Alenina N; Almazov National Medical Research Centre, 2 Akkuratova Str., St-Petersburg 197341, Russia. amalashicheva@gmail.com.
Larionov V; Max-Delbruck Center for Molecular Medicine, 10 Robert-Rössle-Straße, 13125 Berlin, Germany. alenina@mdc-berlin.de.
Kouprina N; Developmental Therapeutics Branch, National Cancer Institute, Bethesda, MD 20892, USA. larionov@mail.nih.gov.
Tomilin AN; Developmental Therapeutics Branch, National Cancer Institute, Bethesda, MD 20892, USA. kouprinn@mail.nih.gov.

Cells ; 7(12)2018 Dec 08.

Article in En | MEDLINE | ID: mdl-30544831

Key words

alphoidtetO-HAC; cell reprogramming; human artificial chromosome (HAC); induced pluripotent stem cells (iPSCs); microcell-mediated chromosome transfer (MMCT)

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