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A novel ASBT inhibitor, IMB17-15, repressed nonalcoholic fatty liver disease development in high-fat diet-fed Syrian golden hamsters.
Ge, Mao-Xu; Niu, Wei-Xiao; Ren, Jin-Feng; Cai, Shi-Ying; Yu, Dong-Ke; Liu, Hong-Tao; Zhang, Na; Zhang, Yi-Xuan; Wang, Yu-Cheng; Shao, Rong-Guang; Wang, Ju-Xian; He, Hong-Wei.
Affiliation
  • Ge MX; NHC Key Laboratory of Biotechnology of Antibiotics, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences, Beijing, 100050, China.
  • Niu WX; NHC Key Laboratory of Biotechnology of Antibiotics, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences, Beijing, 100050, China.
  • Ren JF; NHC Key Laboratory of Biotechnology of Antibiotics, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences, Beijing, 100050, China.
  • Cai SY; Department of Internal Medicine and Liver Center, School of Medicine, Yale University, New Haven, CT, 06520, USA.
  • Yu DK; Department of Internal Medicine and Liver Center, School of Medicine, Yale University, New Haven, CT, 06520, USA.
  • Liu HT; Personalized Drug Therapy Key Laboratory of Sichuan Province, Hospital of the University of Electronic Science and Technology of China and Sichuan Provincial People's Hospital, Chengdu, 610072, China.
  • Zhang N; NHC Key Laboratory of Biotechnology of Antibiotics, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences, Beijing, 100050, China.
  • Zhang YX; Department of Pharmacy, Hebei General Hospital, Shijiazhuang, 050051, China.
  • Wang YC; NHC Key Laboratory of Biotechnology of Antibiotics, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences, Beijing, 100050, China.
  • Shao RG; NHC Key Laboratory of Biotechnology of Antibiotics, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences, Beijing, 100050, China.
  • Wang JX; NHC Key Laboratory of Biotechnology of Antibiotics, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences, Beijing, 100050, China.
  • He HW; NHC Key Laboratory of Biotechnology of Antibiotics, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences, Beijing, 100050, China.
Acta Pharmacol Sin ; 40(7): 895-907, 2019 Jul.
Article in En | MEDLINE | ID: mdl-30573812
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Full text: 1 Database: MEDLINE Main subject: Sulfonamides / Benzamides / Organic Anion Transporters, Sodium-Dependent / Symporters / Non-alcoholic Fatty Liver Disease Limits: Animals / Female / Humans / Male Language: En Journal: Acta Pharmacol Sin Journal subject: FARMACOLOGIA Year: 2019 Type: Article Affiliation country: China
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Full text: 1 Database: MEDLINE Main subject: Sulfonamides / Benzamides / Organic Anion Transporters, Sodium-Dependent / Symporters / Non-alcoholic Fatty Liver Disease Limits: Animals / Female / Humans / Male Language: En Journal: Acta Pharmacol Sin Journal subject: FARMACOLOGIA Year: 2019 Type: Article Affiliation country: China