Renal clearance and intracellular half-life essentially determine methotrexate toxicity: A case series.

Arakawa, Yukiyasu; Arakawa, Akiko; Vural, Secil; Mahajan, Rahul; Prinz, Jörg Christoph.

Affiliation

Arakawa Y; Department of Dermatology, University Clinics, Ludwig-Maximilian-University of Munich, Munich, Germany.
Arakawa A; Department of Dermatology, University Clinics, Ludwig-Maximilian-University of Munich, Munich, Germany.
Vural S; Department of Dermatology, University Clinics, Ludwig-Maximilian-University of Munich, Munich, Germany.
Mahajan R; Department of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Prinz JC; Department of Dermatology, University Clinics, Ludwig-Maximilian-University of Munich, Munich, Germany.

JAAD Case Rep ; 5(1): 98-100, 2019 Jan.

Article in En | MEDLINE | ID: mdl-30581945

Key words

ARF, acute renal failure; MTX, methotrexate; intracellular methotrexate half-life; methotrexate; methotrexate-induced myelosuppression; mucocutaneous adverse events; psoriasis