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Site-Directed Fragment-Based Screening for the Discovery of Protein-Protein Interaction Stabilizers.
Sijbesma, Eline; Hallenbeck, Kenneth K; Leysen, Seppe; de Vink, Pim J; Skóra, Lukasz; Jahnke, Wolfgang; Brunsveld, Luc; Arkin, Michelle R; Ottmann, Christian.
Affiliation
  • Sijbesma E; Laboratory of Chemical Biology, Department of Biomedical Engineering and Institute for Complex Molecular Systems (ICMS) , Eindhoven University of Technology , 5600 MB Eindhoven , The Netherlands.
  • Hallenbeck KK; Department of Pharmaceutical Chemistry and Small Molecule Discovery Centre (SMDC) , University of California , San Francisco 94143 , United States.
  • Leysen S; Laboratory of Chemical Biology, Department of Biomedical Engineering and Institute for Complex Molecular Systems (ICMS) , Eindhoven University of Technology , 5600 MB Eindhoven , The Netherlands.
  • de Vink PJ; Laboratory of Chemical Biology, Department of Biomedical Engineering and Institute for Complex Molecular Systems (ICMS) , Eindhoven University of Technology , 5600 MB Eindhoven , The Netherlands.
  • Skóra L; Chemical Biology and Therapeutics , Novartis Institutes for Biomedical Research , CH-4056 Basel , Switzerland.
  • Jahnke W; Chemical Biology and Therapeutics , Novartis Institutes for Biomedical Research , CH-4056 Basel , Switzerland.
  • Brunsveld L; Laboratory of Chemical Biology, Department of Biomedical Engineering and Institute for Complex Molecular Systems (ICMS) , Eindhoven University of Technology , 5600 MB Eindhoven , The Netherlands.
  • Arkin MR; Department of Pharmaceutical Chemistry and Small Molecule Discovery Centre (SMDC) , University of California , San Francisco 94143 , United States.
  • Ottmann C; Laboratory of Chemical Biology, Department of Biomedical Engineering and Institute for Complex Molecular Systems (ICMS) , Eindhoven University of Technology , 5600 MB Eindhoven , The Netherlands.
J Am Chem Soc ; 141(8): 3524-3531, 2019 02 27.
Article in En | MEDLINE | ID: mdl-30707565
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Full text: 1 Database: MEDLINE Main subject: Breast Neoplasms / 14-3-3 Proteins / Estrogen Receptor alpha / Drug Discovery Type of study: Diagnostic_studies / Screening_studies Limits: Female / Humans Language: En Journal: J Am Chem Soc Year: 2019 Type: Article Affiliation country: Netherlands
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Full text: 1 Database: MEDLINE Main subject: Breast Neoplasms / 14-3-3 Proteins / Estrogen Receptor alpha / Drug Discovery Type of study: Diagnostic_studies / Screening_studies Limits: Female / Humans Language: En Journal: J Am Chem Soc Year: 2019 Type: Article Affiliation country: Netherlands