Working Hours and Risk of Acute Myocardial Infarction and Stroke Among Middle-Aged Japanese Menã- The Japan Public Health Center-Based Prospective Study Cohort II.
Circ J
; 83(5): 1072-1079, 2019 04 25.
Article
in En
| MEDLINE
| ID: mdl-30842356
ABSTRACT
BACKGROUND:
Evidence from prospective cohort studies regarding the relationship between working hours and risk of cardiovascular disease is limited MethodsâandâResults:
The Japan Public Health Center-Based Prospective Study Cohort II involved 15,277 men aged 40-59 years at the baseline survey in 1993. Respondents were followed up until 2012. During the median 20 years of follow up (257,229 person-years), we observed 212 cases of acute myocardial infarction and 745 stroke events. Cox proportional hazards models adjusted for sociodemographic factors, cardiovascular risk factors, and occupation showed that multivariable-adjusted hazard ratios (HRs) associated with overtime work of ≥11h/day were 1.63 (95% confidence interval [CI] 1.01-2.63) for acute myocardial infarction and 0.83 (95% CI 0.60-1.13) for total stroke, as compared with the reference group (working 7 to <9 h/day). In the multivariable model, increased risk of acute myocardial infarction associated with overtime work of ≥11 h/day was more evident among salaried employees (HR 2.11, 95% CI 1.03-4.35) and men aged 50-59 years (HR 2.60, 95% CI 1.42-4.77).CONCLUSIONS:
Among middle-aged Japanese men, working overtime is associated with a higher risk of acute myocardial infarction.Key words
Full text:
1
Database:
MEDLINE
Main subject:
Stroke
/
Work-Life Balance
/
Myocardial Infarction
Type of study:
Clinical_trials
/
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limits:
Adult
/
Humans
/
Male
/
Middle aged
Country/Region as subject:
Asia
Language:
En
Journal:
Circ J
Journal subject:
ANGIOLOGIA
/
CARDIOLOGIA
Year:
2019
Type:
Article