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A Randomized, Double-Blind, Placebo-Controlled, First-Time-in-Human Study to Assess the Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Doses of GSK3389404 in Healthy Subjects.
Han, Kelong; Cremer, Jennifer; Elston, Robert; Oliver, Stuart; Baptiste-Brown, Sharon; Chen, Shuguang; Gardiner, David; Davies, Matt; Saunders, Joanne; Hamatake, Robert; Losos, Jan; Leivers, Martin; Hood, Steve; van der Berg, Frans; Paff, Melanie; Ritter, James M; Theodore, Dickens.
Affiliation
  • Han K; GlaxoSmithKline, Collegeville, Pennsylvania, USA.
  • Cremer J; GlaxoSmithKline, Research Triangle Park, North Carolina, USA.
  • Elston R; GlaxoSmithKline, Stevenage, Hertfordshire, UK.
  • Oliver S; IQVIA, London, UK.
  • Baptiste-Brown S; GlaxoSmithKline, Collegeville, Pennsylvania, USA.
  • Chen S; GlaxoSmithKline, Collegeville, Pennsylvania, USA.
  • Gardiner D; GlaxoSmithKline, Collegeville, Pennsylvania, USA.
  • Davies M; GlaxoSmithKline, Stockley Park, Uxbridge, UK.
  • Saunders J; GlaxoSmithKline, Collegeville, Pennsylvania, USA.
  • Hamatake R; GlaxoSmithKline, Research Triangle Park, North Carolina, USA.
  • Losos J; GlaxoSmithKline, Research Triangle Park, North Carolina, USA.
  • Leivers M; GlaxoSmithKline, Research Triangle Park, North Carolina, USA.
  • Hood S; GlaxoSmithKline, Stevenage, Hertfordshire, UK.
  • van der Berg F; Hammersmith Medicines Research, London, UK.
  • Paff M; GlaxoSmithKline, Beijing, China.
  • Ritter JM; GlaxoSmithKline, Cambridge, UK.
  • Theodore D; GlaxoSmithKline, Research Triangle Park, North Carolina, USA.
Clin Pharmacol Drug Dev ; 8(6): 790-801, 2019 08.
Article in En | MEDLINE | ID: mdl-30861337
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Full text: 1 Database: MEDLINE Main subject: Oligonucleotides, Antisense Type of study: Clinical_trials / Prognostic_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Clin Pharmacol Drug Dev Year: 2019 Type: Article Affiliation country: United States
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Oligonucleotides, Antisense Type of study: Clinical_trials / Prognostic_studies Limits: Adult / Female / Humans / Male / Middle aged Language: En Journal: Clin Pharmacol Drug Dev Year: 2019 Type: Article Affiliation country: United States