Short communication: Inhibition of DNA methyltransferase and histone deacetylase increases ß-defensin expression but not the effects of lipopolysaccharide or 1,25-dihydroxyvitamin D<sub>3</sub> in bovine mammary epithelial cells.

Kweh, Mercedes F; Merriman, Kathryn E; Nelson, Corwin D

Short communication: Inhibition of DNA methyltransferase and histone deacetylase increases ß-defensin expression but not the effects of lipopolysaccharide or 1,25-dihydroxyvitamin D₃ in bovine mammary epithelial cells.

Kweh, Mercedes F; Merriman, Kathryn E; Nelson, Corwin D.

Affiliation

Kweh MF; Animal Molecular and Cellular Biology Graduate Program, University of Florida, Gainesville 32611.
Merriman KE; Animal Molecular and Cellular Biology Graduate Program, University of Florida, Gainesville 32611.
Nelson CD; Department of Animal Sciences, University of Florida, Gainesville 32611. Electronic address: cdnelson@ufl.edu.

J Dairy Sci ; 102(6): 5706-5712, 2019 Jun.

Article in En | MEDLINE | ID: mdl-30954263

Subject(s)

Cattle/metabolism; Epithelial Cells/metabolism; Histone Deacetylases/metabolism; Lipopolysaccharides/metabolism; Mammary Glands, Animal/metabolism; Methyltransferases/metabolism; Vitamin D/analogs & derivatives; beta-Defensins/genetics; Animals; Cattle/genetics; DNA Methylation; Female; Histone Deacetylases/genetics; Mammary Glands, Animal/cytology; Methyltransferases/genetics; Vitamin D/metabolism; beta-Defensins/metabolism

Key words

chromatin remodeling; lipopolysaccharide; mammary immunity; vitamin D; ß-defensin

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Full text: 1 Database: MEDLINE Main subject: Vitamin D / Cattle / Lipopolysaccharides / Beta-Defensins / Epithelial Cells / Histone Deacetylases / Mammary Glands, Animal / Methyltransferases Limits: Animals Language: En Journal: J Dairy Sci Year: 2019 Type: Article

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