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Thrombin: A Gas Pedal Driving Innate Immunity.
Petzold, Tobias; Massberg, Steffen.
Affiliation
  • Petzold T; Medizinische Klinik und Poliklinik I, Klinikum der Universität München, Munich, Germany; DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany.
  • Massberg S; Medizinische Klinik und Poliklinik I, Klinikum der Universität München, Munich, Germany; DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany. Electronic address: steffen.massberg@med.uni-muenchen.de.
Immunity ; 50(4): 1024-1026, 2019 04 16.
Article in En | MEDLINE | ID: mdl-30995493
ABSTRACT
Hemostasis and immunity were long considered entirely separate entities. In this issue of Immunity, Burzynski et al. (2019) find that thrombin, the key enzyme within the coagulation cascade, activates IL-1α, a central pleiotropic pro-inflammatory cytokine, to promote wound healing and platelet production following ectoderm injury.
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Full text: 1 Database: MEDLINE Main subject: Thrombin / Interleukin-1alpha Language: En Journal: Immunity Journal subject: ALERGIA E IMUNOLOGIA Year: 2019 Type: Article Affiliation country: Germany
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Full text: 1 Database: MEDLINE Main subject: Thrombin / Interleukin-1alpha Language: En Journal: Immunity Journal subject: ALERGIA E IMUNOLOGIA Year: 2019 Type: Article Affiliation country: Germany