Adult-onset psychogenic nonepileptic seizures: A multicenter international study.
Epilepsy Behav
; 98(Pt A): 36-39, 2019 09.
Article
in En
| MEDLINE
| ID: mdl-31299530
ABSTRACT
PURPOSE:
The aim of this multicenter international cross-cultural study was to compare clinical variables in a large sample of people with adult-onset psychogenic nonepileptic seizures (PNES).METHODS:
In this retrospective study, we evaluated persons with documented PNES, who were older than 16â¯years of age at the onset, from four countries (i.e., Iran, Brazil, Venezuela, and Argentina) regarding their age, gender, PNES semiology, and possible predisposing factors.RESULTS:
We included 389 patients (244 from Iran, 66 from Brazil, 51 from Venezuela, and 28 from Argentina). Age at diagnosis was 32⯱â¯9â¯years (range 17-64â¯years), and age at the onset of seizures was 27⯱â¯8â¯years (range 17-49â¯years). There was a female predominance in all countries. The demographic characteristics and factors associated with PNES were similar among the countries. However, there were significant semiological differences among the countries.CONCLUSION:
This study corroborates the notion that PNES share more similarities than differences cross-culturally and across international borders. However, the background determined by cultural, ethnic, and religious differences may influence the semiology of PNES. Further cross-cultural studies involving more than two continents may advance our understanding of PNES.Key words
Full text:
1
Database:
MEDLINE
Main subject:
Seizures
Type of study:
Diagnostic_studies
/
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
Limits:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
/
Middle aged
Country/Region as subject:
America do sul
/
Argentina
/
Asia
/
Brasil
Language:
En
Journal:
Epilepsy Behav
Journal subject:
CIENCIAS DO COMPORTAMENTO
/
NEUROLOGIA
Year:
2019
Type:
Article