Loss of BRG1 (<i>SMARCA4</i>) Immunoexpression in a Pediatric Non-Central Nervous System Tumor Cohort.

Saunders, Jessica; Ingley, Katrina; Wang, Xiu Qing; Harvey, Melissa; Armstrong, Linlea; Ng, Tony; Dunham, Christopher; Bush, Jonathan

Loss of BRG1 (SMARCA4) Immunoexpression in a Pediatric Non-Central Nervous System Tumor Cohort.

Saunders, Jessica; Ingley, Katrina; Wang, Xiu Qing; Harvey, Melissa; Armstrong, Linlea; Ng, Tony; Dunham, Christopher; Bush, Jonathan.

Affiliation

Saunders J; Division of Anatomical Pathology, British Columbia Children's Hospital and Women's Hospital and Health Center, Vancouver, British Columbia, Canada.
Ingley K; University of British Columbia, Vancouver, British Columbia, Canada.
Wang XQ; University of British Columbia, Vancouver, British Columbia, Canada.
Harvey M; Division of Pediatric Hematology/Oncology/BMT, British Columbia Children's Hospital and Women's Hospital and Health Center, Vancouver, British Columbia, Canada.
Armstrong L; University of British Columbia, Vancouver, British Columbia, Canada.
Ng T; University of British Columbia, Vancouver, British Columbia, Canada.
Dunham C; Division of Pediatric Hematology/Oncology/BMT, British Columbia Children's Hospital and Women's Hospital and Health Center, Vancouver, British Columbia, Canada.
Bush J; University of British Columbia, Vancouver, British Columbia, Canada.

Pediatr Dev Pathol ; 23(2): 132-138, 2020.

Article in En | MEDLINE | ID: mdl-31403913

Subject(s)

DNA Helicases/metabolism; Nuclear Proteins/metabolism; Rhabdoid Tumor/metabolism; SMARCB1 Protein/metabolism; Transcription Factors/metabolism; Adolescent; Child; Child, Preschool; Cohort Studies; DNA Helicases/genetics; Female; Humans; Immunohistochemistry; Infant; Infant, Newborn; Male; Nuclear Proteins/genetics; Pediatrics; Phenotype; Rhabdoid Tumor/diagnosis; Rhabdoid Tumor/pathology; SMARCB1 Protein/genetics; Transcription Factors/genetics

Key words

BRG1; SMARCA4; malignant rhabdoid tumor

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Full text: 1 Database: MEDLINE Main subject: Transcription Factors / Nuclear Proteins / Rhabdoid Tumor / DNA Helicases / SMARCB1 Protein Type of study: Diagnostic_studies / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Adolescent / Child / Child, preschool / Female / Humans / Infant / Male / Newborn Language: En Journal: Pediatr Dev Pathol Journal subject: PATOLOGIA / PEDIATRIA Year: 2020 Type: Article Affiliation country: Canada

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