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TrkB agonistic antibodies superior to BDNF: Utility in treating motoneuron degeneration.
Guo, Wei; Pang, Keliang; Chen, Yanbo; Wang, Shudan; Li, Heng; Xu, Yihua; Han, Fang; Yao, Hongyang; Liu, Hang; Lopes-Rodrigues, Vanessa; Sun, Dang; Shao, Jingyu; Shen, Jianying; Dou, Yang; Zhang, Wen; You, He; Wu, Wutian; Lu, Bai.
Affiliation
  • Guo W; School of Pharmaceutical Sciences, IDG/McGovern Institute for Brain Research, Tsinghua University, Beijing 100084, China; R&D Center for the Diagnosis and Treatment of Major Brain Diseases, Research Institute of Tsinghua University in Shenzhen, Shenzhen, Guangdong 518057, China.
  • Pang K; School of Pharmaceutical Sciences, IDG/McGovern Institute for Brain Research, Tsinghua University, Beijing 100084, China; R&D Center for the Diagnosis and Treatment of Major Brain Diseases, Research Institute of Tsinghua University in Shenzhen, Shenzhen, Guangdong 518057, China.
  • Chen Y; School of Pharmaceutical Sciences, IDG/McGovern Institute for Brain Research, Tsinghua University, Beijing 100084, China.
  • Wang S; School of Pharmaceutical Sciences, IDG/McGovern Institute for Brain Research, Tsinghua University, Beijing 100084, China; R&D Center for the Diagnosis and Treatment of Major Brain Diseases, Research Institute of Tsinghua University in Shenzhen, Shenzhen, Guangdong 518057, China.
  • Li H; School of Biomedical Sciences, Division of Anatomy, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China.
  • Xu Y; School of Pharmaceutical Sciences, IDG/McGovern Institute for Brain Research, Tsinghua University, Beijing 100084, China; R&D Center for the Diagnosis and Treatment of Major Brain Diseases, Research Institute of Tsinghua University in Shenzhen, Shenzhen, Guangdong 518057, China.
  • Han F; School of Pharmaceutical Sciences, IDG/McGovern Institute for Brain Research, Tsinghua University, Beijing 100084, China; R&D Center for the Diagnosis and Treatment of Major Brain Diseases, Research Institute of Tsinghua University in Shenzhen, Shenzhen, Guangdong 518057, China.
  • Yao H; School of Pharmaceutical Sciences, IDG/McGovern Institute for Brain Research, Tsinghua University, Beijing 100084, China.
  • Liu H; School of Pharmaceutical Sciences, IDG/McGovern Institute for Brain Research, Tsinghua University, Beijing 100084, China; R&D Center for the Diagnosis and Treatment of Major Brain Diseases, Research Institute of Tsinghua University in Shenzhen, Shenzhen, Guangdong 518057, China.
  • Lopes-Rodrigues V; Department of Physiology, National University of Singapore, Singapore; Life Sciences Institute, National University of Singapore, Singapore.
  • Sun D; School of Pharmaceutical Sciences, IDG/McGovern Institute for Brain Research, Tsinghua University, Beijing 100084, China.
  • Shao J; School of Pharmaceutical Sciences, IDG/McGovern Institute for Brain Research, Tsinghua University, Beijing 100084, China.
  • Shen J; School of Pharmaceutical Sciences, IDG/McGovern Institute for Brain Research, Tsinghua University, Beijing 100084, China; Artemisinin Research Center, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100084, China.
  • Dou Y; School of Pharmaceutical Sciences, IDG/McGovern Institute for Brain Research, Tsinghua University, Beijing 100084, China.
  • Zhang W; School of Pharmaceutical Sciences, IDG/McGovern Institute for Brain Research, Tsinghua University, Beijing 100084, China.
  • You H; School of Pharmaceutical Sciences, IDG/McGovern Institute for Brain Research, Tsinghua University, Beijing 100084, China.
  • Wu W; Guangdong-Hong Kong-Macau Institute of CNS Regeneration, Jinan University, Guangzhou, Guangdong Province, China; School of Biomedical Sciences, Division of Anatomy, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China.
  • Lu B; School of Pharmaceutical Sciences, IDG/McGovern Institute for Brain Research, Tsinghua University, Beijing 100084, China; R&D Center for the Diagnosis and Treatment of Major Brain Diseases, Research Institute of Tsinghua University in Shenzhen, Shenzhen, Guangdong 518057, China. Electronic addre
Neurobiol Dis ; 132: 104590, 2019 12.
Article in En | MEDLINE | ID: mdl-31470106
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Full text: 1 Database: MEDLINE Main subject: Neuroprotective Agents / Receptor, trkB / Antibodies, Monoclonal / Motor Neurons / Nerve Degeneration Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Neurobiol Dis Journal subject: NEUROLOGIA Year: 2019 Type: Article Affiliation country: China
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Full text: 1 Database: MEDLINE Main subject: Neuroprotective Agents / Receptor, trkB / Antibodies, Monoclonal / Motor Neurons / Nerve Degeneration Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Neurobiol Dis Journal subject: NEUROLOGIA Year: 2019 Type: Article Affiliation country: China