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Radiosensitization of head and neck squamous cell carcinoma lines by DNA-PK inhibitors is more effective than PARP-1 inhibition and is enhanced by SLFN11 and hypoxia.
Lee, Tet Woo; Wong, Way Wua; Dickson, Benjamin D; Lipert, Barbara; Cheng, Gary J; Hunter, Francis W; Hay, Michael P; Wilson, William R.
Affiliation
  • Lee TW; Auckland Cancer Society Research Centre, University of Auckland, Auckland, New Zealand.
  • Wong WW; Maurice Wilkins Centre for Molecular Biodiscovery, Auckland, New Zealand.
  • Dickson BD; Auckland Cancer Society Research Centre, University of Auckland, Auckland, New Zealand.
  • Lipert B; Auckland Cancer Society Research Centre, University of Auckland, Auckland, New Zealand.
  • Cheng GJ; Auckland Cancer Society Research Centre, University of Auckland, Auckland, New Zealand.
  • Hunter FW; Auckland Cancer Society Research Centre, University of Auckland, Auckland, New Zealand.
  • Hay MP; Auckland Cancer Society Research Centre, University of Auckland, Auckland, New Zealand.
  • Wilson WR; Maurice Wilkins Centre for Molecular Biodiscovery, Auckland, New Zealand.
Int J Radiat Biol ; 95(12): 1597-1612, 2019 12.
Article in En | MEDLINE | ID: mdl-31490091
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Full text: 1 Database: MEDLINE Main subject: Radiation-Sensitizing Agents / Nuclear Proteins / DNA-Activated Protein Kinase / Poly (ADP-Ribose) Polymerase-1 / Tumor Hypoxia / Squamous Cell Carcinoma of Head and Neck Limits: Humans Language: En Journal: Int J Radiat Biol Journal subject: RADIOLOGIA Year: 2019 Type: Article Affiliation country: New Zealand
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Full text: 1 Database: MEDLINE Main subject: Radiation-Sensitizing Agents / Nuclear Proteins / DNA-Activated Protein Kinase / Poly (ADP-Ribose) Polymerase-1 / Tumor Hypoxia / Squamous Cell Carcinoma of Head and Neck Limits: Humans Language: En Journal: Int J Radiat Biol Journal subject: RADIOLOGIA Year: 2019 Type: Article Affiliation country: New Zealand