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3-benzazecine-based cyclic allene derivatives as highly potent P-glycoprotein inhibitors overcoming doxorubicin multidrug resistance.
Titov, Alexander A; Niso, Mauro; Candia, Modesto de; Kobzev, Maxim S; Varlamov, Alexey V; Borisova, Tatiana N; Voskressensky, Leonid G; Colabufo, Nicola A; Cellamare, Saverio; Pisani, Leonardo; Altomare, Cosimo D.
Affiliation
  • Titov AA; Organic Chemistry Department, Peoples' Friendship University of Russia (RUDN University), 6 Miklukho-Maklaya St., Moscow, 117198, Russia.
  • Niso M; Department of Pharmacy-Drug Sciences, University of Bari Aldo Moro, Via E. Orabona 4, 70125 Bari, Italy.
  • Candia M; Department of Pharmacy-Drug Sciences, University of Bari Aldo Moro, Via E. Orabona 4, 70125 Bari, Italy.
  • Kobzev MS; Organic Chemistry Department, Peoples' Friendship University of Russia (RUDN University), 6 Miklukho-Maklaya St., Moscow, 117198, Russia.
  • Varlamov AV; Organic Chemistry Department, Peoples' Friendship University of Russia (RUDN University), 6 Miklukho-Maklaya St., Moscow, 117198, Russia.
  • Borisova TN; Organic Chemistry Department, Peoples' Friendship University of Russia (RUDN University), 6 Miklukho-Maklaya St., Moscow, 117198, Russia.
  • Voskressensky LG; Organic Chemistry Department, Peoples' Friendship University of Russia (RUDN University), 6 Miklukho-Maklaya St., Moscow, 117198, Russia.
  • Colabufo NA; Department of Pharmacy-Drug Sciences, University of Bari Aldo Moro, Via E. Orabona 4, 70125 Bari, Italy.
  • Cellamare S; Department of Pharmacy-Drug Sciences, University of Bari Aldo Moro, Via E. Orabona 4, 70125 Bari, Italy.
  • Pisani L; Department of Pharmacy-Drug Sciences, University of Bari Aldo Moro, Via E. Orabona 4, 70125 Bari, Italy.
  • Altomare CD; Department of Pharmacy-Drug Sciences, University of Bari Aldo Moro, Via E. Orabona 4, 70125 Bari, Italy.
Future Med Chem ; 11(16): 2095-2106, 2019 08.
Article in En | MEDLINE | ID: mdl-31538529
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Full text: 1 Database: MEDLINE Main subject: Aza Compounds / Doxorubicin / ATP Binding Cassette Transporter, Subfamily B, Member 1 / Drug Resistance, Multiple / Alkadienes / Antibiotics, Antineoplastic Limits: Humans Language: En Journal: Future Med Chem Year: 2019 Type: Article Affiliation country: RUSSIA
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Aza Compounds / Doxorubicin / ATP Binding Cassette Transporter, Subfamily B, Member 1 / Drug Resistance, Multiple / Alkadienes / Antibiotics, Antineoplastic Limits: Humans Language: En Journal: Future Med Chem Year: 2019 Type: Article Affiliation country: RUSSIA