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Neutralising anti-drug antibodies in Fabry disease can inhibit endothelial enzyme uptake and activity.
Stappers, Franciska; Scharnetzki, David; Schmitz, Boris; Manikowski, Dominique; Brand, Stefan-Martin; Grobe, Kay; Lenders, Malte; Brand, Eva.
Affiliation
  • Stappers F; Internal Medicine D, Department of Nephrology, Hypertension and Rheumatology, University Hospital Muenster, Muenster, Germany.
  • Scharnetzki D; Internal Medicine D, Department of Nephrology, Hypertension and Rheumatology, University Hospital Muenster, Muenster, Germany.
  • Schmitz B; Institute of Sports Medicine, Molecular Genetics of Cardiovascular Disease, University Hospital Muenster, Muenster, Germany.
  • Manikowski D; Institute of Physiological Chemistry and Pathobiochemistry and Cells-in-Motion Cluster of Excellence (EXC1003-CiM), University of Muenster, Muenster, Germany.
  • Brand SM; Institute of Sports Medicine, Molecular Genetics of Cardiovascular Disease, University Hospital Muenster, Muenster, Germany.
  • Grobe K; Institute of Physiological Chemistry and Pathobiochemistry and Cells-in-Motion Cluster of Excellence (EXC1003-CiM), University of Muenster, Muenster, Germany.
  • Lenders M; Internal Medicine D, Department of Nephrology, Hypertension and Rheumatology, University Hospital Muenster, Muenster, Germany.
  • Brand E; Internal Medicine D, Department of Nephrology, Hypertension and Rheumatology, University Hospital Muenster, Muenster, Germany.
J Inherit Metab Dis ; 43(2): 334-347, 2020 03.
Article in En | MEDLINE | ID: mdl-31587315
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Full text: 1 Database: MEDLINE Main subject: Fabry Disease / Alpha-Galactosidase / Antibodies, Neutralizing / Enzyme Replacement Therapy Limits: Adult / Humans / Male / Middle aged Language: En Journal: J Inherit Metab Dis Year: 2020 Type: Article Affiliation country: Germany
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Fabry Disease / Alpha-Galactosidase / Antibodies, Neutralizing / Enzyme Replacement Therapy Limits: Adult / Humans / Male / Middle aged Language: En Journal: J Inherit Metab Dis Year: 2020 Type: Article Affiliation country: Germany