Vitamin D-fortified cooking oil is an effective way to improve vitamin D status: an institutional efficacy trial.
Eur J Nutr
; 59(6): 2547-2555, 2020 Sep.
Article
in En
| MEDLINE
| ID: mdl-31606753
ABSTRACT
PURPOSE:
High prevalence of vitamin D deficiency (VDD) justifies a cost-effective and sustainable strategy to combat VDD in the community. This study was undertaken for the first time to evaluate the efficacy of daily consumption of vitamin D fortified sunflower oil with a meal.METHODS:
This single-blind trial was conducted in two separate institutions one as intervention (D-fortified sunflower oil) group (DO, n1 = 39) and the other as control (unfortified sunflower oil) group (SO, n2 = 33). Participants consumed their lunches cooked either with D-fortified or unfortified cooking sunflower oil (500 IU/30 g) for 12 weeks. Dietary, anthropometric and biochemical assessments were done for all participants before and after the intervention.RESULTS:
A total of 65 subjects from both sexes aged 32.5 ± 4 years completed the intervention period. Serum 25(OH)D showed a significant increase in DO and a decrease in SO group (8.8 ± 9.3 vs. - 7.4 ± 6.4 ng/mL, p < 0.001). The rise in serum 25(OH)D in DO group was accompanied by a significant decrease in iPTH (DO - 10.2 ± 29.4 vs. SO + 9.2 ± 29.5 pg/mL; p = 0.009). A significant reduction in weight (p = 0.004), BMI (p = 0.029), waist girth (p < 0.001), serum total cholesterol (p = 0.0290) and LDL-C (p = 0.010) was observed in DO, as compared with SO group.CONCLUSIONS:
Cooking oil can be considered as an efficacious vehicle for mass fortification program to combat VDD. The improvement of vitamin D status may bring about betterment of certain cardiometabolic risk factors. REGISTRATION NUMBER Clinicaltrials.gov NCT03826654.Key words
Full text:
1
Database:
MEDLINE
Main subject:
Vitamin D
/
Food, Fortified
/
Nutritional Status
/
Cooking
/
Sunflower Oil
Type of study:
Clinical_trials
/
Risk_factors_studies
Limits:
Adult
/
Female
/
Humans
/
Male
Language:
En
Journal:
Eur J Nutr
Journal subject:
CIENCIAS DA NUTRICAO
Year:
2020
Type:
Article
Affiliation country:
Iran