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MEK inhibition suppresses B regulatory cells and augments anti-tumor immunity.
Yarchoan, Mark; Mohan, Aditya A; Dennison, Lauren; Vithayathil, Teena; Ruggieri, Amanda; Lesinski, Gregory B; Armstrong, Todd D; Azad, Nilofer S; Jaffee, Elizabeth M.
Affiliation
  • Yarchoan M; Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America.
  • Mohan AA; Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America.
  • Dennison L; Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America.
  • Vithayathil T; Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America.
  • Ruggieri A; Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, GA, United States of America.
  • Lesinski GB; Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, GA, United States of America.
  • Armstrong TD; Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America.
  • Azad NS; Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America.
  • Jaffee EM; Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD, United States of America.
PLoS One ; 14(10): e0224600, 2019.
Article in En | MEDLINE | ID: mdl-31671149
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Full text: 1 Database: MEDLINE Main subject: Mitogen-Activated Protein Kinase Kinases / B-Lymphocytes, Regulatory Limits: Animals / Humans / Male Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2019 Type: Article Affiliation country: United States
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Mitogen-Activated Protein Kinase Kinases / B-Lymphocytes, Regulatory Limits: Animals / Humans / Male Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2019 Type: Article Affiliation country: United States