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Botryllamide G is an ABCG2 inhibitor that improves lapatinib delivery in mouse brain.
Strope, Jonathan D; Peer, Cody J; Sissung, Tristan M; Hall, O Morgan; Huang, Phoebe A; Harris, Emily M; Gustafson, Kirk R; Henrich, Curtis J; Sigano, Dina M; Pauly, Gary T; Schneider, Joel P; Bates, Susan E; Figg, William D.
Affiliation
  • Strope JD; Molecular Pharmacology Section, National Cancer Institute, Bethesda, MD, USA.
  • Peer CJ; Clinical Pharmacology Program, National Cancer Institute, Bethesda, MD, USA.
  • Sissung TM; Clinical Pharmacology Program, National Cancer Institute, Bethesda, MD, USA.
  • Hall OM; Clinical Pharmacology Program, National Cancer Institute, Bethesda, MD, USA.
  • Huang PA; Molecular Pharmacology Section, National Cancer Institute, Bethesda, MD, USA.
  • Harris EM; Molecular Pharmacology Section, National Cancer Institute, Bethesda, MD, USA.
  • Gustafson KR; Molecular Targets Program, National Cancer Institute, Frederick, MD, USA.
  • Henrich CJ; Molecular Targets Program, National Cancer Institute, Frederick, MD, USA.
  • Sigano DM; Basic Research Program, Leidos Biomedical Research Inc., Frederick National Laboratory for Cancer Research, Frederick, MD, USA.
  • Pauly GT; Chemical Biology Laboratory, National Cancer Institute, Frederick, MD, USA.
  • Schneider JP; Chemical Biology Laboratory, National Cancer Institute, Frederick, MD, USA.
  • Bates SE; Chemical Biology Laboratory, National Cancer Institute, Frederick, MD, USA.
  • Figg WD; Department of Medicine, Division of Hematology and Oncology, Columbia University, New York, NY, USA.
Cancer Biol Ther ; 21(3): 223-230, 2020.
Article in En | MEDLINE | ID: mdl-31709896
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Full text: 1 Database: MEDLINE Main subject: Phenols / Acrylamides / Brain / Blood-Brain Barrier / ATP Binding Cassette Transporter, Subfamily B / ATP Binding Cassette Transporter, Subfamily G, Member 2 / Lapatinib Limits: Animals Language: En Journal: Cancer Biol Ther Journal subject: NEOPLASIAS / TERAPEUTICA Year: 2020 Type: Article Affiliation country: United States
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Phenols / Acrylamides / Brain / Blood-Brain Barrier / ATP Binding Cassette Transporter, Subfamily B / ATP Binding Cassette Transporter, Subfamily G, Member 2 / Lapatinib Limits: Animals Language: En Journal: Cancer Biol Ther Journal subject: NEOPLASIAS / TERAPEUTICA Year: 2020 Type: Article Affiliation country: United States