Impact of metabolic syndrome on functional outcomes and complications of surgical treatment of prostate cancer.
J Surg Oncol
; 120(8): 1505-1507, 2019 12.
Article
in En
| MEDLINE
| ID: mdl-31721218
ABSTRACT
BACKGROUND:
Metabolic syndrome (MetS) has a negative impact on functional recovery and complications after many surgical procedures.AIM:
To assess the role of Mets on functional outcomes and complications after radical prostatectomy (RP) for prostate cancer. PATIENTS ANDMETHODS:
Complete data were collected from 5758 patients, undergoing RP at a single referral centers in a 10-year period and the presence of MetS before surgery was ascertained in 17.7% of them using a modified version of the IDF-AHA/NHLBI criteria. Outcomes included 1-year continence and potency rates, early (≤90 days) and late (>90 days) complications.RESULTS:
Postoperative continence (no pads) was significantly less likely in MetS patients (75.4% vs 82.6%, P < .01), despite no difference in preoperative continence. Erections with or without therapy were reached in 55.8% of non-MetS and 41.8% of MetS patients (P < .01), in this case a significant difference in preoperative function was seen. No differences in early and late complications, except for wound infections (5.8% vs 3.9%, P < .01) were observed.CONCLUSIONS:
In the present study RP was safe from the complications standpoint in MetS patients, but the presence of the syndrome was a significant risk factor for post-RP incontinence and impotence.Key words
Full text:
1
Database:
MEDLINE
Main subject:
Prostatectomy
/
Prostatic Neoplasms
/
Surgical Wound Infection
/
Urinary Incontinence
/
Metabolic Syndrome
/
Erectile Dysfunction
Type of study:
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
Limits:
Humans
/
Male
/
Middle aged
Language:
En
Journal:
J Surg Oncol
Year:
2019
Type:
Article
Affiliation country:
Italy