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Direct Visualization of Native CRISPR Target Search in Live Bacteria Reveals Cascade DNA Surveillance Mechanism.
Vink, Jochem N A; Martens, Koen J A; Vlot, Marnix; McKenzie, Rebecca E; Almendros, Cristóbal; Estrada Bonilla, Boris; Brocken, Daan J W; Hohlbein, Johannes; Brouns, Stan J J.
Affiliation
  • Vink JNA; Kavli Institute of Nanoscience, Department of Bionanoscience, Delft University of Technology, Van der Maasweg 9, 2629 HZ Delft, the Netherlands.
  • Martens KJA; Laboratory of Biophysics, Wageningen University & Research, Stippeneng 4, 6708 WE Wageningen, the Netherlands; Laboratory of Bionanotechnology, Wageningen University & Research, Bornse Weilanden 9, 6708 WG Wageningen, the Netherlands.
  • Vlot M; Laboratory of Microbiology, Wageningen University & Research, Stippeneng 4, 6708 WE Wageningen, the Netherlands.
  • McKenzie RE; Kavli Institute of Nanoscience, Department of Bionanoscience, Delft University of Technology, Van der Maasweg 9, 2629 HZ Delft, the Netherlands.
  • Almendros C; Kavli Institute of Nanoscience, Department of Bionanoscience, Delft University of Technology, Van der Maasweg 9, 2629 HZ Delft, the Netherlands.
  • Estrada Bonilla B; Kavli Institute of Nanoscience, Department of Bionanoscience, Delft University of Technology, Van der Maasweg 9, 2629 HZ Delft, the Netherlands.
  • Brocken DJW; Leiden Institute of Chemistry, Gorlaeus Laboratories, Leiden University, Leiden, the Netherlands.
  • Hohlbein J; Laboratory of Biophysics, Wageningen University & Research, Stippeneng 4, 6708 WE Wageningen, the Netherlands; Microspectroscopy Research Facility, Wageningen University & Research, Stippeneng 4, 6708 WE Wageningen, the Netherlands. Electronic address: johannes.hohlbein@wur.nl.
  • Brouns SJJ; Kavli Institute of Nanoscience, Department of Bionanoscience, Delft University of Technology, Van der Maasweg 9, 2629 HZ Delft, the Netherlands. Electronic address: stanbrouns@gmail.com.
Mol Cell ; 77(1): 39-50.e10, 2020 01 02.
Article in En | MEDLINE | ID: mdl-31735642
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Full text: 1 Database: MEDLINE Main subject: Bacteria / DNA / RNA, Guide, Kinetoplastida / CRISPR-Associated Proteins / CRISPR-Cas Systems Type of study: Screening_studies Language: En Journal: Mol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2020 Type: Article Affiliation country: Netherlands
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Bacteria / DNA / RNA, Guide, Kinetoplastida / CRISPR-Associated Proteins / CRISPR-Cas Systems Type of study: Screening_studies Language: En Journal: Mol Cell Journal subject: BIOLOGIA MOLECULAR Year: 2020 Type: Article Affiliation country: Netherlands