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Syrbactin proteasome inhibitor TIR-199 overcomes bortezomib chemoresistance and inhibits multiple myeloma tumor growth in vivo.
Pierce, Marquicia R; Robinson, Reeder M; Ibarra-Rivera, Tannya R; Pirrung, Michael C; Dolloff, Nathan G; Bachmann, André S.
Affiliation
  • Pierce MR; Department of Pediatrics and Human Development, College of Human Medicine, Michigan State University, 400 Monroe Ave NW, Grand Rapids, MI 49503, USA.
  • Robinson RM; Department of Cell and Molecular Pharmacology & Experimental Therapeutics, College of Medicine, Medical University of South Carolina, 173 Ashley Ave, Charleston, SC 29425, USA.
  • Ibarra-Rivera TR; Department of Chemistry, University of California-Riverside, Riverside, CA 92521, USA.
  • Pirrung MC; Department of Chemistry, University of California-Riverside, Riverside, CA 92521, USA; Department of Pharmaceutical Sciences, University of California-Irvine, Irvine, CA 92697, USA.
  • Dolloff NG; Department of Cell and Molecular Pharmacology & Experimental Therapeutics, College of Medicine, Medical University of South Carolina, 173 Ashley Ave, Charleston, SC 29425, USA.
  • Bachmann AS; Department of Pediatrics and Human Development, College of Human Medicine, Michigan State University, 400 Monroe Ave NW, Grand Rapids, MI 49503, USA. Electronic address: bachma26@msu.edu.
Leuk Res ; 88: 106271, 2020 01.
Article in En | MEDLINE | ID: mdl-31778912

Full text: 1 Database: MEDLINE Main subject: Azoles / Drug Resistance, Neoplasm / Tumor Burden / Cell Proliferation / Proteasome Inhibitors / Bortezomib / Amides / Multiple Myeloma Limits: Animals / Humans / Male Language: En Journal: Leuk Res Year: 2020 Type: Article Affiliation country: United States

Full text: 1 Database: MEDLINE Main subject: Azoles / Drug Resistance, Neoplasm / Tumor Burden / Cell Proliferation / Proteasome Inhibitors / Bortezomib / Amides / Multiple Myeloma Limits: Animals / Humans / Male Language: En Journal: Leuk Res Year: 2020 Type: Article Affiliation country: United States