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Transcriptional profiling of medulloblastoma with extensive nodularity (MBEN) reveals two clinically relevant tumor subsets with VSNL1 as potent prognostic marker.
Korshunov, Andrey; Okonechnikov, Konstantin; Sahm, Felix; Ryzhova, Marina; Stichel, Damian; Schrimpf, Daniel; Ghasemi, David R; Pajtler, Kristian W; Antonelli, Manila; Donofrio, Vittoria; Mastronuzzi, Angela; Rossi, Sabrina; Camassei, Francesca Diomedi; Buccoliero, Anna Maria; Haberler, Christine; Slavc, Irene; Dahiya, Sonika; Casalini, Belen; Sievers, Philipp; Meyer, Jochen; Kumirova, Ella; Zheludkova, Olga; Golanov, Andrey; Jones, David T W; Pfister, Stefan M; Kool, Marcel; von Deimling, Andreas.
Affiliation
  • Korshunov A; Clinical Cooperation Unit Neuropathology (B300), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany. andrey.korshunov@med.uni-heidelberg.de.
  • Okonechnikov K; Department of Neuropathology, Heidelberg University Hospital, Heidelberg, Germany. andrey.korshunov@med.uni-heidelberg.de.
  • Sahm F; Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany. andrey.korshunov@med.uni-heidelberg.de.
  • Ryzhova M; Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.
  • Stichel D; Division of Pediatric Neurooncology (B062), German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Schrimpf D; Clinical Cooperation Unit Neuropathology (B300), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.
  • Ghasemi DR; Department of Neuropathology, Heidelberg University Hospital, Heidelberg, Germany.
  • Pajtler KW; Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.
  • Antonelli M; Department of Neuropathology, NN Burdenko Neurosurgical Institute, Moscow, Russia.
  • Donofrio V; Clinical Cooperation Unit Neuropathology (B300), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.
  • Mastronuzzi A; Department of Neuropathology, Heidelberg University Hospital, Heidelberg, Germany.
  • Rossi S; Clinical Cooperation Unit Neuropathology (B300), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.
  • Camassei FD; Department of Neuropathology, Heidelberg University Hospital, Heidelberg, Germany.
  • Buccoliero AM; Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.
  • Haberler C; Division of Pediatric Neurooncology (B062), German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Slavc I; Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.
  • Dahiya S; Division of Pediatric Neurooncology (B062), German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Casalini B; Department of radiological oncological and anatomic pathology sciences, Policlinico Umberto I Università Sapienza, Rome, Italy.
  • Sievers P; Pathology Unit, Ospedale Santobono-Pausilipon, Naples, Italy.
  • Meyer J; Department of Onco-Hematology, Cell and Gene Therapy, Bambino Gesù Children's Hospital, Rome, Italy.
  • Kumirova E; Department of Laboratories, Pathology Unit, Bambino Gesù Children's Hospital, Rome, Italy.
  • Zheludkova O; Department of Laboratories, Pathology Unit, Bambino Gesù Children's Hospital, Rome, Italy.
  • Golanov A; Pathology Unit, A. Meyer University Children's Hospital, Florence, Italy.
  • Jones DTW; Institute of Neurology, Medical University of Vienna, Vienna, Austria.
  • Pfister SM; Department of Pediatrics and Adolescent Medicine, Medical University of Vienna, Vienna, Austria.
  • Kool M; Division of Neuropathology, Department of Pathology and Immunology, Washington University in St. Louis, St. Louis, MO, USA.
  • von Deimling A; Clinical Cooperation Unit Neuropathology (B300), German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.
Acta Neuropathol ; 139(3): 583-596, 2020 03.
Article in En | MEDLINE | ID: mdl-31781912
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Full text: 1 Database: MEDLINE Main subject: Biomarkers, Tumor / Cerebellar Neoplasms / Neurocalcin / Medulloblastoma Type of study: Prognostic_studies Limits: Adolescent / Child / Child, preschool / Female / Humans / Infant / Male / Newborn Language: En Journal: Acta Neuropathol Year: 2020 Type: Article Affiliation country: Germany
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Full text: 1 Database: MEDLINE Main subject: Biomarkers, Tumor / Cerebellar Neoplasms / Neurocalcin / Medulloblastoma Type of study: Prognostic_studies Limits: Adolescent / Child / Child, preschool / Female / Humans / Infant / Male / Newborn Language: En Journal: Acta Neuropathol Year: 2020 Type: Article Affiliation country: Germany