Systematic Comparison of Label-Free, SILAC, and TMT Techniques to Study Early Adaption toward Inhibition of EGFR Signaling in the Colorectal Cancer Cell Line DiFi.

Stepath, Markus; Zülch, Birgit; Maghnouj, Abdelouahid; Schork, Karin; Turewicz, Michael; Eisenacher, Martin; Hahn, Stephan; Sitek, Barbara; Bracht, Thilo

Stepath, Markus; Zülch, Birgit; Maghnouj, Abdelouahid; Schork, Karin; Turewicz, Michael; Eisenacher, Martin; Hahn, Stephan; Sitek, Barbara; Bracht, Thilo.

Affiliation

Zülch B; Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie , Universitätsklinikum Knappschaftskrankenhaus Bochum , Bochum 44892 , Germany.

J Proteome Res ; 19(2): 926-937, 2020 02 07.

Article in En | MEDLINE | ID: mdl-31814417

Subject(s)

Colorectal Neoplasms; Proteomics; Cell Line; Colorectal Neoplasms/drug therapy; ErbB Receptors/genetics; Humans; Isotope Labeling

Key words

ERBB3; MAPK; SILAC; TMT; adaptive mechanism; anti-EGFR therapy; cetuximab; colorectal cancer; label-free; phosphoproteomics

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Full text: 1 Database: MEDLINE Main subject: Colorectal Neoplasms / Proteomics Type of study: Prognostic_studies Limits: Humans Language: En Journal: J Proteome Res Journal subject: BIOQUIMICA Year: 2020 Type: Article

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