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Promising New Inhibitors of Tyrosyl-DNA Phosphodiesterase I (Tdp 1) Combining 4-Arylcoumarin and Monoterpenoid Moieties as Components of Complex Antitumor Therapy.
Khomenko, Tatyana M; Zakharenko, Alexandra L; Chepanova, Arina A; Ilina, Ekaterina S; Zakharova, Olga D; Kaledin, Vasily I; Nikolin, Valeriy P; Popova, Nelly A; Korchagina, Dina V; Reynisson, Jóhannes; Chand, Raina; Ayine-Tora, Daniel M; Patel, Jinal; Leung, Ivanhoe K H; Volcho, Konstantin P; Salakhutdinov, Nariman F; Lavrik, Olga I.
Affiliation
  • Khomenko TM; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, 9 acad. Lavrentjev ave., 630090 Novosibirsk, Russia.
  • Zakharenko AL; Novosibirsk Institute of Chemical Biology and Fundamental Medicine, 8, acad. Lavrentjev ave., 630090 Novosibirsk, Russia.
  • Chepanova AA; Novosibirsk Institute of Chemical Biology and Fundamental Medicine, 8, acad. Lavrentjev ave., 630090 Novosibirsk, Russia.
  • Ilina ES; Novosibirsk Institute of Chemical Biology and Fundamental Medicine, 8, acad. Lavrentjev ave., 630090 Novosibirsk, Russia.
  • Zakharova OD; Novosibirsk Institute of Chemical Biology and Fundamental Medicine, 8, acad. Lavrentjev ave., 630090 Novosibirsk, Russia.
  • Kaledin VI; Institute of Cytology and Genetics, 10, acad. Lavrentjev Ave., 630090 Novosibirsk, Russia.
  • Nikolin VP; Institute of Cytology and Genetics, 10, acad. Lavrentjev Ave., 630090 Novosibirsk, Russia.
  • Popova NA; Institute of Cytology and Genetics, 10, acad. Lavrentjev Ave., 630090 Novosibirsk, Russia.
  • Korchagina DV; Novosibirsk State University, V. Zelman Institute for Medicine and Psychology and Department of Natural Sciences, 2, Pirogova str., 630090 Novosibirsk, Russia.
  • Reynisson J; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, 9 acad. Lavrentjev ave., 630090 Novosibirsk, Russia.
  • Chand R; School of Pharmacy and Bioengineering, Keele University, Hornbeam Building, Staffordshire ST5 5BG, UK.
  • Ayine-Tora DM; School of Chemical Sciences, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
  • Patel J; School of Chemical Sciences, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
  • Leung IKH; School of Chemical Sciences, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
  • Volcho KP; School of Chemical Sciences, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand.
  • Salakhutdinov NF; N.N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, 9 acad. Lavrentjev ave., 630090 Novosibirsk, Russia.
  • Lavrik OI; Novosibirsk State University, V. Zelman Institute for Medicine and Psychology and Department of Natural Sciences, 2, Pirogova str., 630090 Novosibirsk, Russia.
Int J Mol Sci ; 21(1)2019 Dec 23.
Article in En | MEDLINE | ID: mdl-31878088
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Full text: 1 Database: MEDLINE Main subject: Phosphodiesterase Inhibitors / Carcinoma, Krebs 2 / Phosphoric Diester Hydrolases / Carcinoma, Lewis Lung / Monoterpenes / Neoplasm Proteins Limits: Animals / Female / Humans / Male Language: En Journal: Int J Mol Sci Year: 2019 Type: Article Affiliation country: RUSSIA
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Phosphodiesterase Inhibitors / Carcinoma, Krebs 2 / Phosphoric Diester Hydrolases / Carcinoma, Lewis Lung / Monoterpenes / Neoplasm Proteins Limits: Animals / Female / Humans / Male Language: En Journal: Int J Mol Sci Year: 2019 Type: Article Affiliation country: RUSSIA