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Single-dose bNAb cocktail or abbreviated ART post-exposure regimens achieve tight SHIV control without adaptive immunity.
Shapiro, Mariya B; Cheever, Tracy; Malherbe, Delphine C; Pandey, Shilpi; Reed, Jason; Yang, Eun Sung; Wang, Keyun; Pegu, Amarendra; Chen, Xuejun; Siess, Don; Burke, David; Henderson, Heidi; Lewinsohn, Rebecca; Fischer, Miranda; Stanton, Jeffrey J; Axthelm, Michael K; Kahl, Christoph; Park, Byung; Lewis, Anne D; Sacha, Jonah B; Mascola, John R; Hessell, Ann J; Haigwood, Nancy L.
Affiliation
  • Shapiro MB; Department of Molecular Microbiology and Immunology, Oregon Health & Science University, Portland, OR, USA.
  • Cheever T; Division of Pathobiology & Immunology, Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.
  • Malherbe DC; Division of Pathobiology & Immunology, Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.
  • Pandey S; University of Texas Medical Branch, Galveston, TX, USA.
  • Reed J; Division of Pathobiology & Immunology, Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.
  • Yang ES; Vaccine & Gene Therapy Institute, Oregon Health & Science University, Beaverton, OR, USA.
  • Wang K; Vaccine Research Center, NIAID/NIH, Bethesda, MD, USA.
  • Pegu A; Vaccine Research Center, NIAID/NIH, Bethesda, MD, USA.
  • Chen X; Vaccine Research Center, NIAID/NIH, Bethesda, MD, USA.
  • Siess D; Vaccine Research Center, NIAID/NIH, Bethesda, MD, USA.
  • Burke D; Molecular Virology Core, Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.
  • Henderson H; Molecular Virology Core, Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.
  • Lewinsohn R; Division of Pathobiology & Immunology, Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.
  • Fischer M; Division of Pathobiology & Immunology, Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.
  • Stanton JJ; Division of Pathobiology & Immunology, Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.
  • Axthelm MK; Division of Comparative Medicine, Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.
  • Kahl C; Division of Pathobiology & Immunology, Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.
  • Park B; Molecular Virology Core, Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.
  • Lewis AD; Atara Biotherapeutics, Thousand Oaks, CA, USA.
  • Sacha JB; Biostatistics & Bioinformatics Core, Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.
  • Mascola JR; Division of Comparative Medicine, Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.
  • Hessell AJ; Department of Molecular Microbiology and Immunology, Oregon Health & Science University, Portland, OR, USA.
  • Haigwood NL; Division of Pathobiology & Immunology, Oregon National Primate Research Center, Oregon Health & Science University, Beaverton, OR, USA.
Nat Commun ; 11(1): 70, 2020 01 07.
Article in En | MEDLINE | ID: mdl-31911610
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Full text: 1 Database: MEDLINE Main subject: HIV Antibodies / Simian Acquired Immunodeficiency Syndrome / Infectious Disease Transmission, Vertical / Anti-HIV Agents / Antibodies, Neutralizing Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2020 Type: Article Affiliation country: United States
Fulltext
Add to My VHL
Print
XML
PubMed Links
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Full text: 1 Database: MEDLINE Main subject: HIV Antibodies / Simian Acquired Immunodeficiency Syndrome / Infectious Disease Transmission, Vertical / Anti-HIV Agents / Antibodies, Neutralizing Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2020 Type: Article Affiliation country: United States