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DAPLE protein inhibits nucleotide exchange on Gαs and Gαq via the same motif that activates Gαi.
Marivin, Arthur; Maziarz, Marcin; Zhao, Jingyi; DiGiacomo, Vincent; Olmos Calvo, Isabel; Mann, Emily A; Ear, Jason; Blanco-Canosa, Juan B; Ross, Elliott M; Ghosh, Pradipta; Garcia-Marcos, Mikel.
Affiliation
  • Marivin A; Department of Biochemistry, Boston University School of Medicine, Boston, Massachusetts 02118.
  • Maziarz M; Department of Biochemistry, Boston University School of Medicine, Boston, Massachusetts 02118.
  • Zhao J; Department of Biochemistry, Boston University School of Medicine, Boston, Massachusetts 02118.
  • DiGiacomo V; Department of Biochemistry, Boston University School of Medicine, Boston, Massachusetts 02118.
  • Olmos Calvo I; Department of Biochemistry, Boston University School of Medicine, Boston, Massachusetts 02118.
  • Mann EA; Department of Biochemistry, Boston University School of Medicine, Boston, Massachusetts 02118.
  • Ear J; Department of Medicine and Cellular and Molecular Medicine, University of California, San Diego, California 92093.
  • Blanco-Canosa JB; Department of Biological Chemistry, Institute for Advanced Chemistry of Catalonia (IQAC-CSIC), Barcelona, Spain 08034.
  • Ross EM; Department of Pharmacology, Green Center for Systems Biology, University of Texas Southwestern Medical Center, Dallas, Texas 75390.
  • Ghosh P; Department of Medicine and Cellular and Molecular Medicine, University of California, San Diego, California 92093.
  • Garcia-Marcos M; Department of Biochemistry, Boston University School of Medicine, Boston, Massachusetts 02118. Electronic address: mgm1@bu.edu.
J Biol Chem ; 295(8): 2270-2284, 2020 02 21.
Article in En | MEDLINE | ID: mdl-31949046
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Full text: 1 Database: MEDLINE Main subject: Guanine Nucleotide Exchange Factors / GTP-Binding Protein alpha Subunits / Intracellular Signaling Peptides and Proteins / Microfilament Proteins Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: J Biol Chem Year: 2020 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Guanine Nucleotide Exchange Factors / GTP-Binding Protein alpha Subunits / Intracellular Signaling Peptides and Proteins / Microfilament Proteins Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: J Biol Chem Year: 2020 Type: Article