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Genomic dissection of 43 serum urate-associated loci provides multiple insights into molecular mechanisms of urate control.
Boocock, James; Leask, Megan; Okada, Yukinori; Matsuo, Hirotaka; Kawamura, Yusuke; Shi, Yongyong; Li, Changgui; Mount, David B; Mandal, Asim K; Wang, Weiqing; Cadzow, Murray; Gosling, Anna L; Major, Tanya J; Horsfield, Julia A; Choi, Hyon K; Fadason, Tayaza; O'Sullivan, Justin; Stahl, Eli A; Merriman, Tony R.
Affiliation
  • Boocock J; Department of Biochemistry, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand.
  • Leask M; Department of Human Genetics, David Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
  • Okada Y; Department of Biochemistry, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand.
  • Matsuo H; Laboratory of Statistical Immunology, Immunology Frontier Research Center (WPI-IFReC), Osaka University, Suita, Japan.
  • Shi Y; Department of Integrative Physiology and Bio-Nano Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan.
  • Li C; Department of Integrative Physiology and Bio-Nano Medicine, National Defense Medical College, Tokorozawa, Saitama, Japan.
  • Mount DB; Bio-X Institutes, Key Laboratory for the Genetics of Developmental and Neuropsychiaric Disorders (Ministry of Education), Shanghai Jiao Tong University, Shanghai, People's Republic of China.
  • Mandal AK; Department of Endocrinology and Metabolism, The Affiliated Hospital of Qingdao University, Qingdao, People's Republic of China.
  • Wang W; Renal Division, Brigham and Women's Hospital, Harvard Medical School, Boston MA, USA.
  • Cadzow M; Renal Division, VA Boston Healthcare System, Harvard Medical School, Boston MA, USA.
  • Gosling AL; Renal Division, Brigham and Women's Hospital, Harvard Medical School, Boston MA, USA.
  • Major TJ; Department of Genetics and Genomic Sciences, Icahn Institute of Genomics and Multiscale Biology, New York, NY, USA.
  • Horsfield JA; Department of Biochemistry, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand.
  • Choi HK; Department of Biochemistry, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand.
  • Fadason T; Department of Biochemistry, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand.
  • O'Sullivan J; Department of Pathology, Otago Medical School, University of Otago, Dunedin, New Zealand.
  • Stahl EA; Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
  • Merriman TR; Liggins Institute, University of Auckland, Auckland, New Zealand.
Hum Mol Genet ; 29(6): 923-943, 2020 04 15.
Article in En | MEDLINE | ID: mdl-31985003
Subject(s)
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Full text: 1 Database: MEDLINE Main subject: Uric Acid / Genetic Markers / Genetic Predisposition to Disease / Polymorphism, Single Nucleotide / Quantitative Trait Loci / Gout Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Limits: Humans Language: En Journal: Hum Mol Genet Journal subject: BIOLOGIA MOLECULAR / GENETICA MEDICA Year: 2020 Type: Article Affiliation country: New Zealand
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Full text: 1 Database: MEDLINE Main subject: Uric Acid / Genetic Markers / Genetic Predisposition to Disease / Polymorphism, Single Nucleotide / Quantitative Trait Loci / Gout Type of study: Observational_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Limits: Humans Language: En Journal: Hum Mol Genet Journal subject: BIOLOGIA MOLECULAR / GENETICA MEDICA Year: 2020 Type: Article Affiliation country: New Zealand