Human artificial chromosomes for pluripotent stem cell-based tissue replacement therapy.

Sinenko, Sergey A; Ponomartsev, Sergey V; Tomilin, Alexey N

Sinenko, Sergey A; Ponomartsev, Sergey V; Tomilin, Alexey N.

Affiliation

Sinenko SA; Institute of Cytology, Russian Academy of Sciences, 4 Tikhoretsky Ave., St-Petersburg, 194064, Russia. Electronic address: s.sinenko@incras.ru.
Ponomartsev SV; Institute of Cytology, Russian Academy of Sciences, 4 Tikhoretsky Ave., St-Petersburg, 194064, Russia.
Tomilin AN; Institute of Cytology, Russian Academy of Sciences, 4 Tikhoretsky Ave., St-Petersburg, 194064, Russia. Electronic address: a.tomilin@incras.ru.

Exp Cell Res ; 389(1): 111882, 2020 04 01.

Article in En | MEDLINE | ID: mdl-32017931

Subject(s)

Chromosomes, Artificial, Human/physiology; Genetic Therapy/methods; Pluripotent Stem Cells/transplantation; Stem Cell Transplantation/methods; Embryonic Stem Cells/physiology; Gene Transfer Techniques; Genetic Therapy/adverse effects; Genetic Therapy/ethics; Humans; Induced Pluripotent Stem Cells/metabolism; Induced Pluripotent Stem Cells/transplantation; Muscular Dystrophy, Duchenne/genetics; Muscular Dystrophy, Duchenne/therapy; Pluripotent Stem Cells/metabolism; Stem Cell Transplantation/adverse effects; Stem Cell Transplantation/ethics

Key words

Embryonic stem cells (ESCs); Gene therapy; Human artificial chromosome (HAC); Induced pluripotent stem cells (iPSCs); MMCT; Tissue replacement therapy

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Full text: 1 Database: MEDLINE Main subject: Genetic Therapy / Chromosomes, Artificial, Human / Pluripotent Stem Cells / Stem Cell Transplantation Limits: Humans Language: En Journal: Exp Cell Res Year: 2020 Type: Article

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