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A Targeted Metabolomics-Based Assay Using Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Identifies Structural and Functional Cardiotoxicity Potential.
Palmer, Jessica A; Smith, Alan M; Gryshkova, Vitalina; Donley, Elizabeth L R; Valentin, Jean-Pierre; Burrier, Robert E.
Affiliation
  • Palmer JA; Stemina Biomarker Discovery, Inc, Madison, Wisconsin.
  • Smith AM; Stemina Biomarker Discovery, Inc, Madison, Wisconsin.
  • Gryshkova V; UCB Biopharma SPRL, Investigative Toxicology, Development Science, B-1420 Braine L'Alleud, Belgium.
  • Donley ELR; Stemina Biomarker Discovery, Inc, Madison, Wisconsin.
  • Valentin JP; UCB Biopharma SPRL, Investigative Toxicology, Development Science, B-1420 Braine L'Alleud, Belgium.
  • Burrier RE; Stemina Biomarker Discovery, Inc, Madison, Wisconsin.
Toxicol Sci ; 174(2): 218-240, 2020 04 01.
Article in En | MEDLINE | ID: mdl-32040181
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Full text: 1 Database: MEDLINE Main subject: Xenobiotics / Myocytes, Cardiac / Drug Discovery / Metabolome / Metabolomics / Induced Pluripotent Stem Cells / Heart Diseases Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Toxicol Sci Journal subject: TOXICOLOGIA Year: 2020 Type: Article
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Full text: 1 Database: MEDLINE Main subject: Xenobiotics / Myocytes, Cardiac / Drug Discovery / Metabolome / Metabolomics / Induced Pluripotent Stem Cells / Heart Diseases Type of study: Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Toxicol Sci Journal subject: TOXICOLOGIA Year: 2020 Type: Article