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Predictive Accuracy of a Polygenic Risk Score Compared With a Clinical Risk Score for Incident Coronary Heart Disease.
Mosley, Jonathan D; Gupta, Deepak K; Tan, Jingyi; Yao, Jie; Wells, Quinn S; Shaffer, Christian M; Kundu, Suman; Robinson-Cohen, Cassianne; Psaty, Bruce M; Rich, Stephen S; Post, Wendy S; Guo, Xiuqing; Rotter, Jerome I; Roden, Dan M; Gerszten, Robert E; Wang, Thomas J.
Affiliation
  • Mosley JD; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
  • Gupta DK; Department of Biomedical Informatics, Vanderbilt University, Nashville, Tennessee.
  • Tan J; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
  • Yao J; Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Department of Pediatrics, Torrance, California.
  • Wells QS; Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Department of Pediatrics, Torrance, California.
  • Shaffer CM; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
  • Kundu S; Department of Pharmacology, Vanderbilt University, Nashville, Tennessee.
  • Robinson-Cohen C; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
  • Psaty BM; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
  • Rich SS; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
  • Post WS; Vanderbilt O'Brien Center for Kidney Disease, Vanderbilt University Medical Center, Nashville, Tennessee.
  • Guo X; Departments of Medicine, Epidemiology and Health Services, University of Washington School of Public Health; and Kaiser Permanente Washington Health Research Institute, Seattle, Washington.
  • Rotter JI; Department of Public Health Sciences, Center for Public Health Genomics, Charlottesville, Virginia.
  • Roden DM; Department of Medicine, Johns Hopkins University, Baltimore, Maryland.
  • Gerszten RE; Department of Epidemiology, Johns Hopkins University, Baltimore, Maryland.
  • Wang TJ; Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Department of Pediatrics, Torrance, California.
JAMA ; 323(7): 627-635, 2020 02 18.
Article in En | MEDLINE | ID: mdl-32068817
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Full text: 1 Database: MEDLINE Main subject: Risk Assessment / Coronary Disease / Genetic Predisposition to Disease / Multifactorial Inheritance Type of study: Etiology_studies / Guideline / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: JAMA Year: 2020 Type: Article
Fulltext
Add to My VHL
Print
XML
PubMed Links
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Full text: 1 Database: MEDLINE Main subject: Risk Assessment / Coronary Disease / Genetic Predisposition to Disease / Multifactorial Inheritance Type of study: Etiology_studies / Guideline / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: JAMA Year: 2020 Type: Article