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Cytolethal distending toxin-induced release of interleukin-1ß by human macrophages is dependent upon activation of glycogen synthase kinase 3ß, spleen tyrosine kinase (Syk) and the noncanonical inflammasome.
Shenker, Bruce J; Walker, Lisa M; Zekavat, Zeyed; Ojcius, David M; Huang, Pei-Rong; Boesze-Battaglia, Kathleen.
Affiliation
  • Shenker BJ; Department of Pathology, University of Pennsylvania School of Dental Medicine, Philadelphia, Pennsylvania, USA.
  • Walker LM; Department of Pathology, University of Pennsylvania School of Dental Medicine, Philadelphia, Pennsylvania, USA.
  • Zekavat Z; Department of Pathology, University of Pennsylvania School of Dental Medicine, Philadelphia, Pennsylvania, USA.
  • Ojcius DM; Department of Biomedical Sciences, University of the Pacific Arthur A. Dugoni School of Dentistry, San Francisco, California, USA.
  • Huang PR; Center for Molecular and Clinical Immunology, Chang Gung University, Taoyuan, Taiwan.
  • Boesze-Battaglia K; Department of Biochemistry, University of Pennsylvania School of Dental Medicine, Philadelphia, Pennsylvania, USA.
Cell Microbiol ; 22(7): e13194, 2020 07.
Article in En | MEDLINE | ID: mdl-32068949
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Full text: 1 Database: MEDLINE Main subject: Bacterial Toxins / Interleukin-1beta / Inflammasomes / Glycogen Synthase Kinase 3 beta / Syk Kinase / Macrophages Limits: Humans Language: En Journal: Cell Microbiol Journal subject: MICROBIOLOGIA Year: 2020 Type: Article Affiliation country: United States
Fulltext
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Full text: 1 Database: MEDLINE Main subject: Bacterial Toxins / Interleukin-1beta / Inflammasomes / Glycogen Synthase Kinase 3 beta / Syk Kinase / Macrophages Limits: Humans Language: En Journal: Cell Microbiol Journal subject: MICROBIOLOGIA Year: 2020 Type: Article Affiliation country: United States