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TLR8 and complement C5 induce cytokine release and thrombin activation in human whole blood challenged with Gram-positive bacteria.
Ehrnström, Birgitta; Kojen, June F; Giambelluca, Miriam; Ryan, Liv; Moen, Siv H; Hu, Zhenyi; Yin, Hang; Mollnes, Tom E; Damås, Jan K; Espevik, Terje; Stenvik, Jørgen.
Affiliation
  • Ehrnström B; Centre of Molecular Inflammation Research, Norwegian University of Science and Technology, Trondheim, Norway.
  • Kojen JF; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.
  • Giambelluca M; Department of Infectious Diseases, Clinic of Medicine, St. Olavs Hospital HF, Trondheim University Hospital, Trondheim, Norway.
  • Ryan L; Centre of Molecular Inflammation Research, Norwegian University of Science and Technology, Trondheim, Norway.
  • Moen SH; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.
  • Hu Z; Centre of Molecular Inflammation Research, Norwegian University of Science and Technology, Trondheim, Norway.
  • Yin H; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.
  • Mollnes TE; Centre of Molecular Inflammation Research, Norwegian University of Science and Technology, Trondheim, Norway.
  • Damås JK; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.
  • Espevik T; Centre of Molecular Inflammation Research, Norwegian University of Science and Technology, Trondheim, Norway.
  • Stenvik J; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.
J Leukoc Biol ; 107(4): 673-683, 2020 04.
Article in En | MEDLINE | ID: mdl-32083344
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Full text: 1 Database: MEDLINE Main subject: Complement C5 / Thrombin / Cytokines / Toll-Like Receptor 8 / Gram-Positive Bacteria Limits: Humans Language: En Journal: J Leukoc Biol Year: 2020 Type: Article Affiliation country: Norway
Fulltext
Add to My VHL
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Full text: 1 Database: MEDLINE Main subject: Complement C5 / Thrombin / Cytokines / Toll-Like Receptor 8 / Gram-Positive Bacteria Limits: Humans Language: En Journal: J Leukoc Biol Year: 2020 Type: Article Affiliation country: Norway