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A guide to naming human non-coding RNA genes.
Seal, Ruth L; Chen, Ling-Ling; Griffiths-Jones, Sam; Lowe, Todd M; Mathews, Michael B; O'Reilly, Dawn; Pierce, Andrew J; Stadler, Peter F; Ulitsky, Igor; Wolin, Sandra L; Bruford, Elspeth A.
Affiliation
  • Seal RL; Department of Haematology, University of Cambridge School of Clinical Medicine, Cambridge, UK.
  • Chen LL; European Molecular Biology Laboratory, European Bioinformatics Institute, Hinxton, UK.
  • Griffiths-Jones S; State Key Laboratory of Molecular Biology, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Science, Shanghai, China.
  • Lowe TM; School of Biological Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
  • Mathews MB; Department of Biomolecular Engineering, University of California, Santa Cruz, CA, USA.
  • O'Reilly D; Department of Medicine, Rutgers New Jersey Medical School, Newark, NJ, USA.
  • Pierce AJ; Computational Biology and Integrative Genomics Lab, MRC/CRUK Oxford Institute and Department of Oncology, University of Oxford, Oxford, UK.
  • Stadler PF; Translational Medicine, Oncology R&D, AstraZeneca, Cambridge, UK.
  • Ulitsky I; Bioinformatics Group, Department of Computer Science, Interdisciplinary Center for Bioinformatics, University of Leipzig, Leipzig, Germany.
  • Wolin SL; Max Planck Institute for Mathematics in the Sciences, Leipzig, Germany.
  • Bruford EA; Institute of Theoretical Chemistry, University of Vienna, Vienna, Austria.
EMBO J ; 39(6): e103777, 2020 03 16.
Article in En | MEDLINE | ID: mdl-32090359
ABSTRACT
Research on non-coding RNA (ncRNA) is a rapidly expanding field. Providing an official gene symbol and name to ncRNA genes brings order to otherwise potential chaos as it allows unambiguous communication about each gene. The HUGO Gene Nomenclature Committee (HGNC, www.genenames.org) is the only group with the authority to approve symbols for human genes. The HGNC works with specialist advisors for different classes of ncRNA to ensure that ncRNA nomenclature is accurate and informative, where possible. Here, we review each major class of ncRNA that is currently annotated in the human genome and describe how each class is assigned a standardised nomenclature.
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Full text: 1 Database: MEDLINE Main subject: Genome, Human / RNA, Untranslated / Terminology as Topic Limits: Humans Language: En Journal: EMBO J Year: 2020 Type: Article Affiliation country: United kingdom
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Full text: 1 Database: MEDLINE Main subject: Genome, Human / RNA, Untranslated / Terminology as Topic Limits: Humans Language: En Journal: EMBO J Year: 2020 Type: Article Affiliation country: United kingdom